RDH12 (NM_152443) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206636L2V

Lenti ORF particles, RDH12 (mGFP-tagged) - Human retinol dehydrogenase 12 (all-trans/9-cis/11-cis) (RDH12), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: RDH12
• Synonyms: LCA13; RP53; SDR7C2
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_152443
• ORF Size: 948 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206636).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_152443.1, NP_689656.1
• RefSeq Size: 1934 bp
• RefSeq ORF: 951 bp
• Locus ID: 145226
• UniProt ID: Q96NR8
• Cytogenetics: 14q24.1
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Retinol metabolism
• MW: 35.1 kDa
• Gene Summary: The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 13 and Retinitis Pigmentosa 53. [provided by RefSeq, Sep 2015]