Rad51L1 (RAD51B) (NM_133509) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC206457L3V
- LentiORF®
Lenti ORF particles, RAD51B (Myc-DDK tagged) - Human RAD51-like 1 (S. cerevisiae) (RAD51L1), transcript variant 3, 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
AAV Particle: DDK
Buy this product and get 50% off on the Lenti RapidTiter kit. Use Code: Rapid50
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USD 365.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | Rad51L1 |
Synonyms | R51H2; RAD51L1; REC2 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_133509 |
ORF Size | 1152 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC206457).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_133509.2 |
RefSeq Size | 2650 bp |
RefSeq ORF | 1155 bp |
Locus ID | 5890 |
UniProt ID | O15315 |
Cytogenetics | 14q24.1 |
Protein Families | Druggable Genome |
Protein Pathways | Homologous recombination |
MW | 42.2 kDa |
Gene Summary | The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016] |
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