AXL (NM_021913) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206431L2V

Lenti ORF particles, AXL (mGFP-tagged) - Human AXL receptor tyrosine kinase (AXL), transcript variant 1, 200ul, >10^7 TU/mL

Product Images

RC206431L2 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC206431L2V particle to overexpress human AXL-mGFP fusion protein.

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  RC206431L2 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC206431L2V particle to overexpress human AXL-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: AXL
• Synonyms: ARK; JTK11; Tyro7; UFO
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_021913
• ORF Size: 2682 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206431).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_021913.2
• RefSeq Size: 5014 bp
• RefSeq ORF: 2685 bp
• Locus ID: 558
• UniProt ID: P30530
• Cytogenetics: 19q13.2
• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• MW: 98.2 kDa
• Gene Summary: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]