GPSM2 (NM_013296) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC205650L3V

Lenti ORF particles, GPSM2 (Myc-DDK tagged) - Human G-protein signaling modulator 2 (GPSM2), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: GPSM2
• Synonyms: CMCS; DFNB82; LGN; PINS
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_013296
• ORF Size: 2031 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205650).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_013296.4, NP_037428.2
• RefSeq Size: 3039 bp
• RefSeq ORF: 2055 bp
• Locus ID: 29899
• UniProt ID: P81274
• Cytogenetics: 1p13.3
• Domains: TPR, GoLoco
• Protein Families: Druggable Genome
• MW: 75.8 kDa
• Gene Summary: The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]