MANBA (NM_005908) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204862L4V

Lenti ORF particles, MANBA (mGFP-tagged) - Human mannosidase, beta A, lysosomal (MANBA), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: MANBA
• Synonyms: MANB1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_005908
• ORF Size: 2637 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204862).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005908.3
• RefSeq Size: 3311 bp
• RefSeq ORF: 2640 bp
• Locus ID: 4126
• UniProt ID: O00462
• Cytogenetics: 4q24
• Domains: Glyco_hydro_2_C
• Protein Pathways: Lysosome, Other glycan degradation
• MW: 100.9 kDa
• Gene Summary: This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement. [provided by RefSeq, Jul 2008]