RHBDF2 (NM_024599) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC203923L3V

Lenti ORF particles, RHBDF2 (Myc-DDK tagged) - Human rhomboid 5 homolog 2 (Drosophila) (RHBDF2), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: RHBDF2
• Synonyms: iRhom2; RHBDL5; RHBDL6; TEC; TOC; TOCG
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_024599
• ORF Size: 2568 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203923).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_024599.2, NP_078875.2
• RefSeq Size: 3615 bp
• RefSeq ORF: 2571 bp
• Locus ID: 79651
• UniProt ID: Q6PJF5
• Cytogenetics: 17q25.1
• Protein Families: Protease, Transmembrane
• MW: 96.7 kDa
• Gene Summary: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.[UniProtKB/Swiss-Prot Function]