ICA1 (NM_004968) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202149L3V

Lenti ORF particles, ICA1 (Myc-DDK tagged) - Human islet cell autoantigen 1, 69kDa (ICA1), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: ICA1
• Synonyms: ICA69; ICAp69
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_004968
• ORF Size: 1446 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202149).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004968.2, NP_004959.2
• RefSeq Size: 2396 bp
• RefSeq ORF: 1452 bp
• Locus ID: 3382
• UniProt ID: Q05084
• Cytogenetics: 7p21.3
• Domains: ICA69
• Protein Pathways: Type I diabetes mellitus
• MW: 54.5 kDa
• Gene Summary: This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]