GPBB (PYGB) (NM_002862) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202077L3V

Lenti ORF particles, PYGB (Myc-DDK tagged) - Human phosphorylase, glycogen; brain (PYGB), 200ul, >10^7 TU/mL

Product Images

RC202077L3 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC202077L3V particle to overexpress human PYGB-Myc-DDK fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: GPBB
• Synonyms: GPBB
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_002862
• ORF Size: 2529 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202077).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002862.3
• RefSeq Size: 4131 bp
• RefSeq ORF: 2532 bp
• Locus ID: 5834
• UniProt ID: P11216
• Cytogenetics: 20p11.21
• Domains: phosphorylase
• Protein Families: Druggable Genome
• Protein Pathways: Insulin signaling pathway, Starch and sucrose metabolism
• MW: 96.7 kDa
• Gene Summary: The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq, Jul 2008]