Methylmalonyl Coenzyme A mutase (MUT) (NM_000255) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201972L2V

Lenti ORF particles, MUT (mGFP-tagged) - Human methylmalonyl CoA mutase (MUT), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Methylmalonyl Coenzyme A mutase
• Synonyms: MCM; MUT
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_000255
• ORF Size: 2250 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201972).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000255.1
• RefSeq Size: 3886 bp
• RefSeq ORF: 2253 bp
• Locus ID: 4594
• UniProt ID: P22033
• Cytogenetics: 6p12.3
• Domains: MM_CoA_mutase, B12-binding
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation
• MW: 83.2 kDa
• Gene Summary: This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria. [provided by RefSeq, Jul 2008]