Phosphoribosyl pyrophosphate amidotransferase (PPAT) (NM_002703) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201144L1V

Lenti ORF particles, PPAT (Myc-DDK tagged) - Human phosphoribosyl pyrophosphate amidotransferase (PPAT), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Phosphoribosyl pyrophosphate amidotransferase
• Synonyms: ATASE; GPAT; PRAT
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_002703
• ORF Size: 1551 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201144).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002703.3
• RefSeq Size: 3713 bp
• RefSeq ORF: 1554 bp
• Locus ID: 5471
• UniProt ID: Q06203
• Cytogenetics: 4q12
• Domains: GATase_2, Pribosyltran
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Alanine, aspartate and glutamate metabolism, Metabolic pathways, Purine metabolism
• MW: 57.4 kDa
• Gene Summary: The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq, Mar 2011]