DUSP14 (NM_007026) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200531L2V

Lenti ORF particles, DUSP14 (mGFP-tagged) - Human dual specificity phosphatase 14 (DUSP14), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: DUSP14
• Synonyms: MKP-L; MKP6
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_007026
• ORF Size: 594 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200531).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007026.1
• RefSeq Size: 1508 bp
• RefSeq ORF: 597 bp
• Locus ID: 11072
• UniProt ID: O95147
• Cytogenetics: 17q12
• Domains: DSPc
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: MAPK signaling pathway
• MW: 22.3 kDa
• Gene Summary: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]