TXNL4A (NM_006701) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200266L3V

Lenti ORF particles, TXNL4A (Myc-DDK tagged) - Human thioredoxin-like 4A (TXNL4A), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: TXNL4A
• Synonyms: BMKS; DIB1; DIM1; SNRNP15; TXNL4; U5-15kD
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_006701
• ORF Size: 426 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200266).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006701.2
• RefSeq Size: 1415 bp
• RefSeq ORF: 429 bp
• Locus ID: 10907
• UniProt ID: P83876
• Cytogenetics: 18q23
• Domains: DIM1
• Protein Families: Druggable Genome
• Protein Pathways: Spliceosome
• MW: 16.8 kDa
• Gene Summary: The protein encoded by this gene is a member of the U5 small ribonucleoprotein particle (snRNP), and is involved in pre-mRNA splicing. This protein contains a thioredoxin-like fold and it is expected to interact with multiple proteins. Protein-protein interactions have been observed with the polyglutamine tract-binding protein 1 (PQBP1). Mutations in both the coding region and promoter region of this gene have been associated with Burn-McKeown syndrome, which is a rare disorder characterized by craniofacial dysmorphisms, cardiac defects, hearing loss, and bilateral choanal atresia. A pseudogene of this gene is found on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]