Ptprc (NM_001111316) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR227276L4V

Lenti ORF particles, Ptprc (GFP-tagged) - Mouse protein tyrosine phosphatase, receptor type, C (Ptprc), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Ptprc
• Synonyms: B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4; T200
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001111316
• ORF Size: 3879 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR227276).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001111316.2, NP_001104786.2
• RefSeq Size: 5664 bp
• RefSeq ORF: 3882 bp
• Locus ID: 19264
• UniProt ID: P06800
• Cytogenetics: 1 60.73 cM
• Gene Summary: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity.[UniProtKB/Swiss-Prot Function]