Nox4 (NM_015760) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR227192L3V

Lenti ORF particles, Nox4 (Myc-DDK-tagged) - Mouse NADPH oxidase 4 (Nox4), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Nox4
• Synonyms: AI648021
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_015760
• ORF Size: 1734 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR227192).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_015760.5, NP_056575.1
• RefSeq Size: 3760 bp
• RefSeq ORF: 1737 bp
• Locus ID: 50490
• UniProt ID: Q9JHI8
• Cytogenetics: 7 D3
• Gene Summary: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.[UniProtKB/Swiss-Prot Function]