Egfr (NM_207655) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR226160L3V

Reviews ()
Write a review
  • LentiORF®

Lenti ORF particles, Egfr (Myc-DDK-tagged) - Mouse epidermal growth factor receptor (Egfr), transcript variant 1, 200ul, >10^7 TU/mL



Interest in protein/lysate? Submit request here!

Get anti-DDK tag antibody at $68 with code “DDK”. View details.

USD 2,064.00


Availability*
5 Weeks

Size
    • 200 ul


Product images

Specifications

Product Data
Product Name Egfr (NM_207655) Mouse Tagged ORF Clone Lentiviral Particle
Type Mouse Tagged ORF Clone
Tag Myc-DDK
Symbol Egfr
Synonyms 9030024J15Rik; AI552599; Erbb; Errb1; Errp; wa-2; wa2; Wa5
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_207655
ORF Size 3630 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR226160).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_207655.2, NP_997538.1
RefSeq Size 5983 bp
RefSeq ORF 3633 bp
Locus ID 13649
UniProt ID Q9WVF5, Q9EP98, Q3TQS6, Q01279
Cytogenetics 11 9.41 cM
Gene Summary Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:8404850). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin (By similarity). Plays a role in enhancing learning and memory performance (PubMed:20639532).[UniProtKB/Swiss-Prot Function]
Other products for "Egfr"
Frequently bought together (2)
Lenti ORF control particles of pLenti-C-Myc-DDK-P2A-Puro, >1x10^7 TU/ml, 0.5 ml
    • 500 ul

USD 341.00


One-Wash Lentivirus Titer Kit, HIV-1 p24 ELISA
    • 96 reactions

USD 627.00

Customer Reviews 
Loading...
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Molbio tools