Ibtk (NM_001081282) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR224109L3V
- LentiORF®
Lenti ORF particles, Ibtk (Myc-DDK-tagged) - Mouse inhibitor of Bruton agammaglobulinemia tyrosine kinase (Ibtk), 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
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USD 365.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Ibtk |
Synonyms | 5430411K16Rik; AA409502; BTKI; mKIAA1417 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001081282 |
ORF Size | 4056 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR224109).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001081282.1, NP_001074751.1 |
RefSeq Size | 5679 bp |
RefSeq ORF | 4059 bp |
Locus ID | 108837 |
UniProt ID | Q6ZPR6 |
Cytogenetics | 9 E3.1 |
Gene Summary | Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. Down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription (By similarity).[UniProtKB/Swiss-Prot Function] |
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