Dbnl (NM_001146309) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR223599L4V

  • LentiORF®

Lenti ORF particles, Dbnl (GFP-tagged) - Mouse drebrin-like (Dbnl), transcript variant 3, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK w/ Puro mGFP w/ Puro



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USD 1,053.00

7 Weeks*

Size
    • 200 ul

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Specifications

Product Data
Type Mouse Tagged ORF Clone
Tag mGFP
Symbol Dbnl
Synonyms Abp1; mAbp1; SH3P7
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_001146309
ORF Size 1296 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR223599).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001146309.1, NP_001139781.1
RefSeq Size 2357 bp
RefSeq ORF 1299 bp
Locus ID 13169
UniProt ID Q62418
Cytogenetics 11 3.87 cM
Gene Summary Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.[UniProtKB/Swiss-Prot Function]

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