Zeb1 (NM_011546) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR223095L4V

Lenti ORF particles, Zeb1 (GFP-tagged) - Mouse zinc finger E-box binding homeobox 1 (Zeb1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Zeb1
• Synonyms: 3110032K11Rik; AREB6; BZP; MEB1; Nil2; TCF-8; Tcf8; Tcf18; Tw; ZEB; Zfhep; Zfhx1a; Zfx1a; Zfx1ha
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_011546
• ORF Size: 3354 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR223095).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_011546.2, NP_035676.1
• RefSeq Size: 5806 bp
• RefSeq ORF: 3354 bp
• Locus ID: 21417
• UniProt ID: Q64318
• Cytogenetics: 18 A1
• Gene Summary: Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1 (By similarity). Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.[UniProtKB/Swiss-Prot Function]