Bace2 (NM_019517) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR220631L4V

Lenti ORF particles, Bace2 (GFP-tagged) - Mouse beta-site APP-cleaving enzyme 2 (Bace2), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Bace2
• Synonyms: 1110059C24Rik; A; AEPLC; AI850424; AL; ALP56; ARP1; AS; ASP1; ASP21; BAE; BAE2; CDA1; CDA13; CEA; CEAP1; DRAP
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_019517
• ORF Size: 1542 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR220631).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_019517.4, NP_062390.3
• RefSeq Size: 3736 bp
• RefSeq ORF: 1545 bp
• Locus ID: 56175
• UniProt ID: Q9JL18
• Cytogenetics: 16 C4
• Gene Summary: This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein undergoes proteolytic processing to generate an active endopeptidase enzyme. This transmembrane protease catalyzes the proteolysis of amyloid precursor protein to produce amyloid beta peptide. Mice lacking the encoded product exhibit increased pancreatic beta cell mass and improved glucose tolerance due to increased insulin secretion. [provided by RefSeq, Jul 2016]