Smox (NM_001177833) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR219787L4V

Lenti ORF particles, Smox (GFP-tagged) - Mouse spermine oxidase (Smox), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Smox
• Synonyms: B130066H01Rik; PAO; PAOh1; SMO
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001177833
• ORF Size: 1755 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR219787).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001177833.1, NP_001171304.1
• RefSeq Size: 2280 bp
• RefSeq ORF: 1758 bp
• Locus ID: 228608
• UniProt ID: Q99K82
• Cytogenetics: 2 F1
• Gene Summary: Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.[UniProtKB/Swiss-Prot Function]