Dnajb6 (NM_011847) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR219417L4V
- LentiORF®
Lenti ORF particles, Dnajb6 (GFP-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily B, member 6 (Dnajb6), transcript variant 3, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
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USD 365.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Dnajb6 |
Synonyms | HSJ-2; mDj4; Mrj |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_011847 |
ORF Size | 726 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR219417).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_011847.4, NP_035977.2 |
RefSeq Size | 1645 bp |
RefSeq ORF | 729 bp |
Locus ID | 23950 |
UniProt ID | O54946 |
Cytogenetics | 5 B1 |
Gene Summary | Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins (By similarity). Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity (By similarity).[UniProtKB/Swiss-Prot Function] |
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