Erlin1 (NM_145502) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR217210L4V

Lenti ORF particles, Erlin1 (GFP-tagged) - Mouse ER lipid raft associated 1 (Erlin1), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Erlin1
• Synonyms: 2810439N09Rik; C80197; Keo4; Spfh1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_145502
• ORF Size: 1041 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR217210).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_145502.3, NP_663477.3
• RefSeq Size: 3349 bp
• RefSeq ORF: 1047 bp
• Locus ID: 226144
• UniProt ID: Q91X78
• Cytogenetics: 19 C3
• Gene Summary: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex (By similarity).[UniProtKB/Swiss-Prot Function]