Slit1 (NM_015748) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR212022L3V

Lenti ORF particles, Slit1 (Myc-DDK-tagged) - Mouse slit homolog 1 (Drosophila) (Slit1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Slit1
• Synonyms: mKIAA0813; Slil1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_015748
• ORF Size: 4593 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR212022).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_015748.3, NP_056563.2
• RefSeq Size: 5300 bp
• RefSeq ORF: 4596 bp
• Locus ID: 20562
• UniProt ID: Q80TR4
• Cytogenetics: 19 C3
• Gene Summary: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.[UniProtKB/Swiss-Prot Function]