Card11 (NM_175362) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR211717L3V

Lenti ORF particles, Card11 (Myc-DDK-tagged) - Mouse caspase recruitment domain family, member 11 (Card11), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Card11
• Synonyms: 0610008L17Rik; 2410011D02Rik; BIMP3; CARMA1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_175362
• ORF Size: 3462 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR211717).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_175362.2, NP_780571.2
• RefSeq Size: 4112 bp
• RefSeq ORF: 3465 bp
• Locus ID: 108723
• UniProt ID: Q8CIS0
• Cytogenetics: 5 G2
• Gene Summary: Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation (PubMed:12356734, PubMed:16356855). Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. Also activates the TORC1 signaling pathway (By similarity).[UniProtKB/Swiss-Prot Function]