Card14 (NM_130886) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR211416L4V
- LentiORF®
Lenti ORF particles, Card14 (GFP-tagged) - Mouse caspase recruitment domain family, member 14 (Card14), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
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USD 365.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Card14 |
Synonyms | Bimp2; CARMA2 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_130886 |
ORF Size | 2997 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR211416).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_130886.3 |
RefSeq Size | 3958 bp |
RefSeq ORF | 3000 bp |
Locus ID | 170720 |
UniProt ID | Q99KF0 |
Cytogenetics | 11 E2 |
Gene Summary | Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1, and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14-induced activation of NF-kappa-B and p38/JNK MAP kinases. May play a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis.[UniProtKB/Swiss-Prot Function] |
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