Elmo2 (NM_207706) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR210342L4V

Lenti ORF particles, Elmo2 (GFP-tagged) - Mouse engulfment and cell motility 2, ced-12 homolog (C. elegans) (Elmo2), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Elmo2
• Synonyms: 1190002F24Rik; CED-12
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_207706
• ORF Size: 2199 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR210342).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_207706.1, NP_997589.1
• RefSeq Size: 4636 bp
• RefSeq ORF: 2199 bp
• Locus ID: 140579
• UniProt ID: Q8BHL5
• Cytogenetics: 2 H3
• Gene Summary: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity).[UniProtKB/Swiss-Prot Function]