Frk (NM_001159544) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR208226L3V

Lenti ORF particles, Frk (Myc-DDK-tagged) - Mouse fyn-related kinase (Frk), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Frk
• Synonyms: BSK; BSK/IYK; C85044; GTK; RAK
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001159544
• ORF Size: 1539 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR208226).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001159544.1, NP_001153016.1
• RefSeq Size: 4825 bp
• RefSeq ORF: 1539 bp
• Locus ID: 14302
• UniProt ID: Q922K9
• Cytogenetics: 10 B1
• Gene Summary: Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity).[UniProtKB/Swiss-Prot Function]