Lpcat3 (NM_145130) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR207801L4V

Lenti ORF particles, Lpcat3 (GFP-tagged) - Mouse lysophosphatidylcholine acyltransferase 3 (Lpcat3), 200ul, >10^7 TU/mL

Product Images

MR207801L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with MR207801L4V particle to overexpress human Lpcat3-mGFP fusion protein.

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Lpcat3
• Synonyms: C3f; Grcc3f; Lpcat; Lpeat; Lplat5; Lpsat; Mboat5; Moact5; Oact5; PTG
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_145130
• ORF Size: 1464 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR207801).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_145130.1
• RefSeq Size: 2502 bp
• RefSeq ORF: 1464 bp
• Locus ID: 14792
• UniProt ID: Q91V01
• Cytogenetics: 6 59.17 cM
• Gene Summary: Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity). To a lesser extent, also catalyzes the acylation of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity), and the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine or PS) (LPSAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Seems to be the major enzyme contributing to LPCAT activity in the liver. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.[UniProtKB/Swiss-Prot Function]