Amotl2 (NM_019764) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR207385L3V
- LentiORF®
Lenti ORF particles, Amotl2 (Myc-DDK-tagged) - Mouse angiomotin-like 2 (Amotl2), 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
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USD 365.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Amotl2 |
Synonyms | AW549739; C79691; Lccp; MASCOT; mKIAA0989 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_019764 |
ORF Size | 2319 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR207385).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_019764.2, NP_062738.2 |
RefSeq Size | 4191 bp |
RefSeq ORF | 2319 bp |
Locus ID | 56332 |
UniProt ID | Q8K371 |
Cytogenetics | 9 F1 |
Gene Summary | Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC (By similarity).[UniProtKB/Swiss-Prot Function] |
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