Noxo1 (NM_027988) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR205276L2V

Lenti ORF particles, Noxo1 (GFP-tagged) - Mouse NADPH oxidase organizer 1 (Noxo1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Noxo1
• Synonyms: 2310034C04Rik; hslt; P41NOX; P41NOXA; P41NOXB; P41NOXC; Snx28
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_027988
• ORF Size: 1050 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR205276).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_027988.4, NP_082264.2
• RefSeq Size: 2239 bp
• RefSeq ORF: 1050 bp
• Locus ID: 71893
• UniProt ID: Q8VCM2
• Cytogenetics: 17 12.49 cM
• Gene Summary: Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. Isoform 3 is more potent than isoform 1 in activating NOX3. Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activity.[UniProtKB/Swiss-Prot Function]