Irf2 (NM_008391) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR205275L3V

Lenti ORF particles, Irf2 (Myc-DDK-tagged) - Mouse interferon regulatory factor 2 (Irf2), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Irf2
• Synonyms: 9830146E22Rik; AI646973; Irf-2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_008391
• ORF Size: 1047 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR205275).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_008391.4, NP_032417.3
• RefSeq Size: 2484 bp
• RefSeq ORF: 1050 bp
• Locus ID: 16363
• UniProt ID: P23906
• Cytogenetics: 8 B1.1
• Gene Summary: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.[UniProtKB/Swiss-Prot Function]