Hax1 (NM_011826) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR203783L3V

Lenti ORF particles, Hax1 (Myc-DDK-tagged) - Mouse HCLS1 associated X-1 (Hax1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Hax1
• Synonyms: HAX-1; Hs1bp1; HSP1BP-1; mHAX-1s; SIG-111; Silg111
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_011826
• ORF Size: 843 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR203783).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_011826.3, NP_035956.1
• RefSeq Size: 1175 bp
• RefSeq ORF: 843 bp
• Locus ID: 23897
• UniProt ID: O35387
• Cytogenetics: 3 F1
• Gene Summary: Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.[UniProtKB/Swiss-Prot Function]