Tmem119 (NM_146162) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR203782L4V
- LentiORF®
Lenti ORF particles, Tmem119 (GFP-tagged) - Mouse transmembrane protein 119 (Tmem119), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
AAV Particle: DDK
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USD 365.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Tmem119 |
Synonyms | AW208946; BC025600; obif |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_146162 |
ORF Size | 843 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR203782).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_146162.1 |
RefSeq Size | 2132 bp |
RefSeq ORF | 843 bp |
Locus ID | 231633 |
UniProt ID | Q8R138 |
Cytogenetics | 5 F |
Gene Summary | Plays an important role in bone formation and normal bone mineralization (PubMed:26207632, PubMed:22416756, PubMed:20025746). Promotes the differentiation of myoblasts into osteoblasts (PubMed:22416756, PubMed:20025746, PubMed:22579779). May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway (PubMed:21239498, PubMed:22579779). Upregulates the expression of ATF4 which plays a central role in osteoblast differentiation (PubMed:24362451). Essential for normal spermatogenesis and late testicular differentiation (PubMed:26207632).[UniProtKB/Swiss-Prot Function] |
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