CYFIP1 (NM_001287810) Human Untagged Clone

CAT#: SC337970

CYFIP1 (untagged) - Human cytoplasmic FMR1 interacting protein 1 (CYFIP1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CYFIP1
• Synonyms: P140SRA-1; SHYC; SRA-1; SRA1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001287810, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGCCCAGGTGACTCTGGAGGACGCGCTGTCCAACGTGGACCTCCTGGAGGAGCTGCCCCTGCCCG
  ACCAGCAGCCCTGCATCGAGCCCCCGCCATCCTCGCTGCTCTACCAGCCAAATTTCAACACTAACTTTGA
  AGACAGAAATGCATTTGTTACTGGCATCGCAAGATACATTGAACAAGCCACCGTCCACTCTAGCATGAAC
  GAGATGCTGGAGGAGGGCCAAGAATATGCTGTCATGCTGTACACCTGGAGGAGCTGCTCCCGGGCCATCC
  CACAGGTGAAATGTAACGAGCAGCCTAACAGAGTGGAAATCTACGAGAAAACCGTGGAGGTTCTGGAGCC
  TGAGGTCACAAAACTGATGAATTTCATGTACTTCCAGAGAAATGCCATTGAGCGTTTCTGCGGGGAAGTG
  AGGCGCCTGTGCCATGCCGAGAGGAGGAAGGACTTCGTGTCAGAAGCCTACCTGATCACACTGGGCAAAT
  TCATCAACATGTTCGCTGTGCTGGACGAGCTGAAGAACATGAAGTGCAGTGTGAAGAACGACCACTCAGC
  GTACAAGAGGGCCGCTCAGTTTTTACGTAAAATGGCAGATCCACAGTCCATCCAGGAATCGCAGAATCTG
  TCCATGTTCCTGGCCAATCATAACAAGATCACACAGTCTCTGCAGCAGCAGCTCGAAGTGATTTCTGGCT
  ACGAAGAGCTCCTGGCAGATATTGTGAATCTGTGTGTGGATTACTACGAGAACAGGATGTATTTGACGCC
  CAGTGAGAAACACATGCTTCTCAAAGTCATGGGATTTGGTCTGTACCTGATGGATGGGAGTGTCAGTAAC
  ATCTATAAGTTGGATGCCAAGAAAAGAATAAACTTATCCAAAATCGACAAGTACTTCAAGCAACTCCAGG
  TGGTTCCGCTATTTGGGGACATGCAAATAGAACTGGCAAGATATATCAAGACCAGCGCCCACTACGAGGA
  AAATAAATCTCGATGGACGTGCACATCCTCCGGCAGCAGCCCTCAGTACAACATCTGCGAGCAGATGATC
  CAGATCCGCGAGGACCACATGCGCTTCATTTCGGAGCTGGCGCGCTACAGCAACAGCGAGGTGGTCACGG
  GCTCGGGCCGCCAGGAGGCCCAGAAGACGGACGCGGAGTACCGCAAGCTCTTCGACCTGGCGCTGCAGGG
  CCTGCAGCTGTTGTCGCAGTGGAGCGCGCACGTGATGGAAGTGTATTCCTGGAAGCTTGTGCACCCCACC
  GACAAGTACTCCAACAAGGACTGCCCCGACAGCGCTGAAGAGTACGAGCGTGCCACGCGCTACAACTACA
  CCAGCGAGGAGAAGTTTGCCCTAGTGGAGGTGATCGCCATGATCAAAGGCCTGCAGGTGCTGATGGGCAG
  GATGGAGAGCGTGTTCAACCACGCCATCCGGCACACCGTCTATGCCGCACTGCAGGACTTCTCCCAGGTG
  ACCCTTAGGGAGCCGCTGCGGCAGGCCATCAAGAAGAAGAAGAACGTCATCCAGAGTGTCCTGCAGGCCA
  TCAGGAAGACCGTGTGTGACTGGGAGACGGGGCATGAGCCCTTCAATGACCCAGCCTTGCGGGGCGAGAA
  GGACCCCAAGAGCGGCTTCGACATAAAAGTACCACGCCGCGCCGTGGGACCCTCCAGCACTCAGCTTTAC
  ATGGTGAGAACCATGCTAGAGTCCCTCATTGCAGACAAAAGTGGTTCCAAGAAAACCTTGAGAAGTAGCC
  TTGAGGGGCCCACCATATTGGACATAGAAAAATTTCATCGAGAGTCATTCTTCTACACTCACTTGATAAA
  TTTCAGTGAAACGCTGCAGCAGTGCTGTGACCTTTCGCAGCTGTGGTTCCGAGAGTTCTTCCTGGAGCTG
  ACCATGGGCAGGAGGATCCAGTTCCCCATTGAGATGTCGATGCCCTGGATCCTGACGGACCACATCCTGG
  AGACCAAGGAGGCATCGATGATGGAGTACGTGCTCTACTCCCTGGACCTGTACAATGACAGCGCCCACTA
  CGCGCTCACCAGGTTCAACAAGCAGTTCCTGTACGACGAAATTGAGGCCGAGGTGAATCTATGTTTTGAC
  CAATTTGTTTACAAGCTAGCAGACCAGATATTTGCCTATTATAAGGTTATGGCAGGAAGTTTGCTTCTTG
  ATAAACGGTTACGATCAGAATGCAAGAATCAGGGAGCCACGATCCACCTCCCGCCGTCTAACCGCTACGA
  GACGCTGCTGAAGCAGAGGCATGTGCAGCTCCTCGGCAGATCAATAGACCTCAATCGTCTGATCACCCAG
  CGCGTCTCAGCAGCCATGTATAAGTCCCTAGAACTGGCGATTGGACGATTTGAAAGTGAAGATTTGACCT
  CCATAGTTGAGCTGGATGGCCTGTTGGAAATCAACCGCATGACCCACAAGCTGCTGAGCCGGTACCTGAC
  GCTGGACGGCTTCGACGCCATGTTCCGGGAGGCCAACCACAACGTGTCAGCGCCCTACGGGAGGATCACC
  CTGCACGTCTTCTGGGAGCTCAACTATGACTTCCTGCCCAACTACTGCTACAACGGCTCTACCAACCGGT
  TTGTTCGGACAGTGTTACCATTTTCTCAGGAATTTCAAAGAGATAAGCAGCCTAATGCACAGCCTCAGTA
  TCTGCATGGATCCAAGGCTTTGAACTTGGCCTACTCCAGCATTTACGGCAGCTACCGGAACTTCGTGGGA
  CCTCCACACTTTCAAGTCATCTGCCGGCTTCTCGGCTACCAGGGTATCGCCGTGGTCATGGAGGAGCTGC
  TGAAGGTCGTCAAGAGCCTGCTGCAAGGCACAATCCTGCAGTACGTGAAGACGCTGATGGAGGTGATGCC
  CAAGATCTGCCGCCTGCCCCGGCACGAGTACGGCTCTCCTGGTATCCTGGAGTTCTTCCACCACCAGCTG
  AAGGACATCGTGGAGTACGCAGAGCTGAAGACGGTGTGCTTCCAGAACCTGCGGGAGGTGGGGAACGCCA
  TCCTCTTCTGCCTGCTCATCGAGCAGAGCCTGTCTTTAGAAGAAGTGTGTGACCTGCTGCACGCGGCTCC
  TTTCCAGAACATCTTGCCGCGAGTCCATGTGAAAGAGGGGGAGAGACTTGATGCCAAAATGAAAAGACTA
  GAATCAAAGTACGCCCCGCTGCATCTTGTCCCACTGATTGAAAGACTGGGGACCCCTCAGCAAATTGCCA
  TCGCAAGAGAGGGGGACCTGCTGACAAAGGAGCGCCTCTGCTGCGGCCTGTCCATGTTTGAGGTCATCCT
  GACACGGATCCGGAGCTTTCTGGATGACCCCATCTGGCGCGGGCCTCTGCCCAGCAATGGGGTCATGCAT
  GTGGACGAGTGTGTGGAGTTTCACAGACTGTGGAGTGCCATGCAGTTTGTCTACTGCATTCCCGTGGGGA
  CACACGAGTTCACAGTCGAGCAGTGCTTTGGTGATGGGCTACACTGGGCTGGCTGTATGATCATCGTACT
  TCTTGGGCAGCAGCGGCGTTTTGCTGTGCTGGATTTCTGCTACCATCTACTTAAAGTCCAGAAACATGAT
  GGCAAAGATGAGATTATTAAAAATGTGCCTTTGAAGAAGATGGTGGAGAGAATTCGCAAGTTCCAGATTC
  TCAATGATGAGATCATCACCATCCTGGATAAGTACCTGAAGTCAGGCGACGGGGAGGGCACGCCAGTGGA
  GCATGTGCGCTGCTTCCAGCCGCCCATCCACCAGTCCCTCGCCAGCAGCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001287810
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001287810.1, NP_001274739.1
• RefSeq Size: 4600 bp
• RefSeq ORF: 3762 bp
• Locus ID: 23191
• UniProt ID: Q7L576
• Cytogenetics: 15q11.2
• Protein Pathways: Regulation of actin cytoskeleton
• Gene Summary: This gene encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization.This protein also interacts with the Fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion. [provided by RefSeq, May 2017]
  Transcript Variant: This variant (2), as well as variants 1, 3, and 4, encodes isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.