AMSH (STAMBP) (NM_006463) Human Untagged Clone

CAT#: SC321959

STAMBP (untagged)-Human STAM binding protein (STAMBP), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AMSH
• Synonyms: AMSH; MICCAP
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC321959 GGTGGGGCAGGGCCTCCGAGCGTGGTTGGACTTTGAAGGGGATCGGCCGCCGTGAGTGTG
  GGGCCTGCAGCCTACTCTCCCCGAGTCCCCTGCCCGGCCTGCCTCGCTCGAGGCACCCGA
  CGGCTTCTGTCTCCGCGGGCTGGCGCCTGACCAGCCAGGCCCAGCGGTTCCCCGCCTACT
  GCATTTGAAAGATCCCGAAAACCCTGGATGATTGTGCCTGGGGTTGGCAAGTTCGTCTTG
  AGTGCCTTCAAGAAGGGTTCCTCAAGCAGTTGTCGATAGAGCCCTCCCTACTGTATACGC
  CCCCTCCGCTCATTCCTGCTACTTCCTTTCTCCTCCTCGTATTTCCCCCTCGGTCCTTTA
  CGCCGCCTTTCCCCCTCATTTGCAGATGCTGCATCCCCTTTTTGGAATTGCTCAACCAGG
  TGGTAACCGGCGCCGCTTCCTGGCCTTGGGAGGTGGTTCCTTTCTTAACCCACAAGAACC
  TCTCCCAAGAGAACTTGGTCCTGATGTCTGACCATGGAGATGTGAGCCTCCCGCCCGAAG
  ACCGGGTGAGGGCTCTCTCCCAGCTGGGTAGTGCGGTAGAGGTGAATGAAGACATTCCAC
  CCCGTCGGTACTTCCGCTCTGGAGTTGAGATTATCCGAATGGCATCCATTTACTCTGAGG
  AAGGCAACATTGAACATGCCTTCATCCTCTATAACAAGTATATCACGCTCTTTATTGAGA
  AACTACCAAAACATCGAGATTACAAATCTGCTGTCATTCCTGAAAAGAAAGACACAGTAA
  AGAAATTAAAGGAGATTGCATTTCCCAAAGCAGAAGAGCTGAAGGCAGAGCTGTTAAAAC
  GATATACCAAAGAATATACAGAATATAATGAAGAAAAGAAGAAGGAAGCAGAGGAATTGG
  CCCGGAACATGGCCATCCAGCAAGAGCTGGAAAAGGAAAAACAGAGGGTAGCACAACAGA
  AGCAGCAGCAATTGGAACAGGAACAGTTCCATGCCTTCGAGGAGATGATCCGGAACCAGG
  AGCTAGAAAAAGAGCGACTGAAAATTGTACAGGAGTTTGGGAAGGTAGACCCTGGCCTAG
  GTGGCCCGCTAGTGCCTGACTTGGAGAAGCCCTCCTTAGATGTGTTCCCCACCTTAACAG
  TCTCATCCATACAGCCTTCAGACTGTCACACAACTGTAAGGCCAGCTAAGCCACCTGTGG
  TGGACAGGTCCTTGAAACCTGGAGCACTGAGCAACTCAGAAAGTATTCCCACAATCGATG
  GATTGCGCCATGTGGTGGTGCCTGGGCGGCTGTGCCCACAGTTTCTCCAGTTAGCCAGTG
  CCAACACTGCCCGGGGAGTGGAGACATGTGGAATTCTCTGTGGAAAACTGATGAGGAATG
  AATTTACCATTACCCATGTTCTCATCCCCAAGCAAAGTGCTGGGTCTGATTACTGCAACA
  CAGAGAACGAAGAAGAACTTTTCCTCATACAGGATCAGCAGGGCCTCATCACACTGGGCT
  GGATTCATACTCACCCCACACAGACCGCGTTTCTCTCCAGTGTCGACCTACACACTCACT
  GCTCTTACCAGATGATGTTGCCAGAGTCAGTAGCCATTGTTTGCTCCCCCAAGTTCCAGG
  AAACTGGATTCTTTAAACTAACTGACCATGGACTAGAGGAGATTTCTTCCTGTCGCCAGA
  AAGGATTTCATCCACACAGCAAGGATCCACCTCTGTTCTGTAGCTGCAGCCACGTGACTG
  TTGTGGACAGAGCAGTGACCATCACAGACCTTCGATGAGCGTTTGAGTCCAACACCTTCC
  AAGAACAACAAAACCATATCAGTGTACTGTAGCCCCTTAATTTAAGCTTTCTAGAAAGCT
  TTGGAAGTTTTTGTAGATAGTAGAAAGGGGGGCATCACCTGAGAAAGAGCTGATTTTGTA
  TTTCAGGTTTGAAAAGAAATAACTGAACATATTTTTTAGGCAAGTCAGAAAGAGAACATG
  GTCACCCAAAAGCAACTGTAACTCAGAAATTAAGTTACTCAGAAATTAAGTAGCTCAGAA
  ATTAAGAAAGAATGGTATAATGAACCCCCATATACCCTTCCTTCTGGATTCACCAATTGT
  TAACATTTTTTTCCTCTCAGCTATCCTTCTAATTTCTCTCTAATTTCAATTTGTTTATAT
  TTACCTCTGGGCTCAATAAGGGCATCTGTGCAGAAATTTGGAAGCCATTTAGAAAATCTT
  TTGGATTTTCCTGTGGTTTATGGCAATATGAATGGAGCTTATTACTGGGGTGAGGGACAG
  CTTACTCCATTTGACCAGATTGTTTGGCTAACACATCCCGAAGAATGATTTTGTCAGGAA
  TTATTGTTATTTAATAAATATTTCAGGATATTTTTCCTCTACAATAAAGTAACAATTAAC
  TTAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_006463
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006463.3, NP_006454.1
• RefSeq Size: 2106 bp
• RefSeq ORF: 1275 bp
• Locus ID: 10617
• UniProt ID: O95630
• Cytogenetics: 2p13.1
• Domains: JAB_MPN
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis
• Gene Summary: Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Variants 1, 2 and 3 encode the same protein.