SEPTIN6 (NM_145799) Human Untagged Clone

CAT#: SC320536

41523 (untagged)-Human septin 6 (SEPT6), transcript variant I

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SEPTIN6
• Synonyms: SEP2; SEPT2; SEPT6
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_145799.2 GGCGGCACCCGTGGCAGCCCTGGCGGACGCAGGAGCGATGGCAGCGACCGATATAGCTCG
  CCAGGTGGGTGAAGGTTGCCGAACTGTCCCCCTGGCTGGACATGTGGGGTTTGACAGCTT
  GCCTGACCAGCTGGTGAATAAGTCCGTCAGCCAGGGCTTCTGCTTCAACATCCTGTGCGT
  GGGAGAGACAGGTTTGGGCAAGTCCACCCTCATGGACACCCTGTTCAACACCAAATTCGA
  AGGGGAGCCAGCCACCCACACACAGCCGGGTGTCCAGCTCCAGTCTAATACCTATGACCT
  CCAAGAGAGCAACGTGAGGCTAAAGCTCACGATCGTTAGCACAGTTGGCTTTGGGGACCA
  GATCAACAAAGAGGACAGCTACAAGCCTATCGTGGAATTCATCGATGCACAATTCGAGGC
  CTACCTGCAGGAAGAGCTAAAGATCCGAAGAGTGCTACACACCTACCATGACTCCCGAAT
  CCATGTCTGCTTGTATTTCATTGCCCCCACGGGTCATTCCCTGAAGTCTCTGGACCTAGT
  GACTATGAAGAAGCTGGACAGTAAGGTGAACATCATCCCCATCATTGCCAAAGCAGATGC
  CATTTCGAAGAGTGAGCTAACAAAGTTCAAAATCAAAATCACCAGCGAGCTTGTCAGCAA
  CGGAGTCCAGATCTATCAGTTTCCTACAGATGATGAGTCGGTGGCAGAGATCAATGGAAC
  CATGAACGCCCACCTGCCGTTTGCTGTCATTGGCAGCACAGAAGAACTGAAGATAGGCAA
  CAAGATGATGAGGGCGCGGCAGTATCCTTGGGGCACTGTGCAGGTTGAAAACGAGGCCCA
  CTGCGACTTTGTGAAGCTGCGGGAGATGCTGATTCGGGTCAACATGGAGGATCTGCGGGA
  GCAGACCCACACCCGGCACTATGAGCTGTATCGCCGCTGTAAGCTGGAGGAGATGGGCTT
  CAAGGACACCGACCCTGACAGCAAACCCTTCAGTTTACAGGAGACACATGAGGCCAAAAG
  GAACGAGTTCCTAGGGGAACTCCAGAAAAAAGAAGAGGAGATGAGACAGATGTTCGTCCA
  GCGAGTCAAAGAGAAAGAAGCGGAGCTCAAAGAGGCAGAGAAAGAGCTGCACGAGAAGTT
  TGACCGTCTGAAGAAACTGCACCAGGACGAGAAGAAGAAACTGGAGGATAAGAAGAAATC
  CCTGGATGATGAAGTGAATGCTTTCAAGCAAAGAAAGACGGCGGCTGAGCTGCTCCAGTC
  CCAGGGCTCCCAGGCTGGAGGCTCACAGACTCTGAAGAGAGACAAAGAGAAGAAAAATTA
  ACTCTGCTGTTTGCTGCATGCTGCATGAGACCCAGGGTCCTGTTTGGGCTTCCTGTAGAC
  ACCCTTTTCCTGCGCAACAGAGCTGGGCCTCCCTTTCTCTAATTTCCCCCTTAACATGCC
  TGGGGGGCATACAATCCAACCCGCGCCCTCTCCTCTCTTCCTGCCAAGGTTTATAGAAAC
  CTGAGAATCTGAGGGTGATGTCTGGCCGCTGGTCAAGAAGCCAACAGTCATGTGGCTCGC
  AGATGCATCCTGCATCCCAGTCCCCCTCCCAGCACCCCCAGCCATCCCCCCTGTCTTCCC
  CCACATCTTTGCCAGAGGTGTGACATGGTCAGGGGGCCCATCTGCTACTCTTTCCCACCA
  GCTCCCCTGTTCCAGTTCTGGTTGCTGTTAGTTTCCCTGAGGTATTTGCAACCACCATGG
  CTGGGTAACCACCGATCAGCACAGCTGTCCCCTTGGTCTCCTGTATCCCAGTCACTAGTC
  CTCCCTGGTCCACCCCACCCTCATCCTCAGGAGCCACAGCCATTTCTTAGAGGGTTTCAA
  AAGGACAGCCTTTGGCGCCTTTTCCTTCTAACCTTTGAGTCCAGCCCTTTCCAGTTTTCA
  TTCACTCGAAGTAACTGCACTCAAGCTGTGCTCAAAATCGGCAACGCATTTATTTACACC
  AAGCCCTTCCCATAAAACACAACTGCTGAAGAAAATAGCAGACGTTTCCCCTCTCTCTAA
  CTCTGGGTATCCCACAGATGCAAAAGGGAGAATAAACCTGAATATTATTAAAAAAAAAAA
  AAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_145799
• Insert Size: 2050 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_145799.2, NP_665798.1
• RefSeq Size: 4716 bp
• RefSeq ORF: 1284 bp
• Locus ID: 23157
• UniProt ID: Q14141
• Cytogenetics: Xq24
• Gene Summary: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (I) contains an additional segment in the 3' coding region, which leads to a frameshift and immediate translation termination, as compared to variant II. The resulting isoform (A) is truncated at the C-terminus, as compared to isoform B. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.