C3AR1 (NM_004054) Human Untagged Clone

CAT#: SC319736

C3AR1 (untagged)-Human complement component 3a receptor 1 (C3AR1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: C3AR1
• Synonyms: AZ3B; C3AR; HNFAG09
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004054.2 ACTGTGGCTAAGTGTGGGGACCAGACAGGACTCGTGGAGACATCCAGGTGCTGAAGCCTT
  CAGCTACTGTCTCAGTTTTTTGAAGTTTAGCAATGGCGTCTTTCTCTGCTGAGACCAATT
  CAACTGACCTACTCTCACAGCCATGGAATGAGCCCCCAGTAATTCTCTCCATGGTCATTC
  TCAGCCTTACTTTTTTACTGGGATTGCCAGGCAATGGGCTGGTGCTGTGGGTGGCTGGCC
  TGAAGATGCAGCGGACAGTGAACACAATTTGGTTCCTCCACCTCACCTTGGCGGACCTCC
  TCTGCTGCCTCTCCTTGCCCTTCTCGCTGGCTCACTTGGCTCTCCAGGGACAGTGGCCCT
  ACGGCAGGTTCCTATGCAAGCTCATCCCCTCCATCATTGTCCTCAACATGTTTGCCAGTG
  TCTTCCTGCTTACTGCCATTAGCCTGGATCGCTGTCTTGTGGTATTCAAGCCAATCTGGT
  GTCAGAATCATCGCAATGTAGGGATGGCCTGCTCTATCTGTGGATGTATCTGGGTGGTGG
  CTTTTGTGATGTGCATTCCTGTGTTCGTGTACCGGGAAATCTTCACTACAGACAACCATA
  ATAGATGTGGCTACAAATTTGGTCTCTCCAGCTCATTAGATTATCCAGACTTTTATGGAG
  ATCCACTAGAAAACAGGTCTCTTGAAAACATTGTTCAGCCGCCTGGAGAAATGAATGATA
  GGTTAGATCCTTCCTCTTTCCAAACAAATGATCATCCTTGGACAGTCCCCACTGTCTTCC
  AACCTCAAACATTTCAAAGACCTTCTGCAGATTCACTCCCTAGGGGTTCTGCTAGGTTAA
  CAAGTCAAAATCTGTATTCTAATGTATTTAAACCTGCTGATGTGGTCTCACCTAAAATCC
  CCAGTGGGTTTCCTATTGAAGATCACGAAACCAGCCCACTGGATAACTCTGATGCTTTTC
  TCTCTACTCATTTAAAGCTGTTCCCTAGCGCTTCTAGCAATTCCTTCTACGAGTCTGAGC
  TACCACAAGGTTTCCAGGATTATTACAATTTAGGCCAATTCACAGATGACGATCAAGTGC
  CAACACCCCTCGTGGCAATAACGATCACTAGGCTAGTGGTGGGTTTCCTGCTGCCCTCTG
  TTATCATGATAGCCTGTTACAGCTTCATTGTCTTCCGAATGCAAAGGGGCCGCTTCGCCA
  AGTCTCAGAGCAAAACCTTTCGAGTGGCCGTGGTGGTGGTGGCTGTCTTTCTTGTCTGCT
  GGACTCCATACCACATTTTTGGAGTCCTGTCATTGCTTACTGACCCAGAAACTCCCTTGG
  GGAAAACTCTGATGTCCTGGGATCATGTATGCATTGCTCTAGCATCTGCCAATAGTTGCT
  TTAATCCCTTCCTTTATGCCCTCTTGGGGAAAGATTTTAGGAAGAAAGCAAGGCAGTCCA
  TTCAGGGAATTCTGGAGGCAGCCTTCAGTGAGGAGCTCACACGTTCCACCCACTGTCCCT
  CAAACAATGTCATTTCAGAAAGAAATAGTACAACTGTGTGAAAATGTGGAGCAGCCAACA
  AGCAGGGGCTCTTAGGCAATCACATAGTGAAAGTTTATAAGAGGATGAAGTGATATGGTG
  AGCAGCGGACTTCAAAAACTGTCAAAGAATCAATCCAGCGGTTCTCAAACGGTACACAGA
  CTATTGACATCAGCATCACCTAGAAACTTGTTAGAAATGCAAATTCTCAAGCCGCATCCC
  AGACTTGCTGAATCGGAATCTCTGGGGGTTGGGACCCAGCAAGGGCACTTAACAAACCCT
  CGTTTCTGATTAATGCTAAATGTAAGAATCATTGTAAACATTAGTTCTATTTCTATCCCA
  AACTAAGCTATGTGAAATAAGAGAAGCTACTTTGTTTTTAAATGATGTTGAATATTTGTC
  GATATTTCCATCATTAAATTTTTCCTTAGCATTGTAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAA
• Restriction Sites: Please inquire
• ACCN: NM_004054
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004054.2, NP_004045.1
• RefSeq Size: 1985 bp
• RefSeq ORF: 1449 bp
• Locus ID: 719
• UniProt ID: Q16581
• Cytogenetics: 12p13.31
• Domains: 7tm_1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Complement and coagulation cascades, Neuroactive ligand-receptor interaction
• Gene Summary: C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization. [provided by RefSeq, May 2016]
  Transcript Variant: This variant (1) represents the predominant transcript. All three variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.