WDR5 (NM_052821) Human Untagged Clone

CAT#: SC319466

WDR5 (untagged)-Human WD repeat domain 5 (WDR5), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WDR5
• Synonyms: BIG-3; CFAP89; SWD3
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_052821.3 GCCTTGTCGAGCTGAGTCCGCGCTCCCGCCCAGGCGGCGGCCGACGCGACGCCCCGAGCG
  CCCGGCCCCGCCGCCGCGGCCCGGCAGACTGCCTCTGTCACCGGGTCCCTCCACCCTTGT
  CTCCTGTGCGGCCAGCATCAGAGCCATGGCGACGGAGGAGAAGAAGCCCGAGACCGAGGC
  CGCCAGAGCACAGCCAACCCCTTCGTCATCCGCCACTCAGAGCAAGCCTACACCTGTGAA
  GCCAAACTATGCTCTAAAGTTCACCCTTGCTGGCCACACCAAAGCAGTGTCCTCCGTGAA
  ATTCAGCCCGAATGGAGAGTGGCTGGCAAGTTCATCTGCTGATAAACTTATTAAAATTTG
  GGGCGCGTATGATGGGAAATTTGAGAAAACCATATCTGGTCACAAGCTGGGAATATCCGA
  TGTAGCCTGGTCGTCAGATTCTAACCTTCTTGTTTCTGCCTCAGATGACAAAACCTTGAA
  GATATGGGACGTGAGCTCGGGCAAGTGTCTGAAAACCCTGAAGGGACACAGTAATTATGT
  CTTTTGCTGCAACTTCAATCCCCAGTCCAACCTTATTGTCTCAGGATCCTTTGACGAAAG
  CGTGAGGATATGGGATGTGAAAACAGGGAAGTGCCTCAAGACTTTGCCAGCTCACTCGGA
  TCCAGTCTCGGCCGTTCATTTTAATCGTGATGGATCCTTGATAGTTTCAAGTAGCTATGA
  TGGTCTCTGTCGCATCTGGGACACCGCCTCGGGCCAGTGCCTGAAGACGCTCATCGATGA
  CGACAACCCCCCCGTGTCTTTTGTGAAGTTCTCCCCGAACGGCAAATACATCCTGGCCGC
  CACGCTGGACAACACTCTGAAGCTCTGGGACTACAGCAAGGGGAAGTGCCTGAAGACGTA
  CACTGGCCACAAGAATGAGAAATACTGCATATTTGCCAATTTCTCTGTTACTGGTGGGAA
  GTGGATTGTGTCTGGCTCAGAGGATAACCTTGTTTACATCTGGAACCTTCAGACGAAAGA
  GATTGTACAGAAACTACAAGGCCACACAGATGTCGTGATCTCAACAGCTTGTCACCCAAC
  AGAAAACATCATCGCCTCTGCTGCGCTAGAAAATGACAAAACAATTAAACTGTGGAAGAG
  TGACTGCTAAGTCCCTTTGCTCCTGCCCGCAAGAGACTGTCGGGAAGTTGACCCGGATTG
  GCAAGAAACAGGGTGTCTTGGAGGTGGTCCCCCAGATCTGCGCCTGGGGGTCAGGACAGG
  GCCTGATTTGAGCCTCCTCTCTGAAGATGATTTGGCCGAGCGGAAGGTGTGGACCACCAG
  AAAGTTCTTAAAAGTTGCTGGTGACATTTCTTGCCAATTCTAACACTGTCTAGGGAAGAG
  TTCCTAGTCTATTGTGTTCAAACAGAGTCAACAAAAGTTTTTAATTTTTTATTACAGAAG
  GGTGAAGTTCAATTTAACATGCGTTGTGTTTTTTCAGTAAACGTTCTGTATCTTTTTGAT
  ATTCCATGACCCAGTGCACGCTGTGGCCTGTCACCGCCACCGTGGCCCCGCCAGCTGGCC
  TCCCCTTTGGCCCACGCCGGCCGCCCCCATTCTCTGCTGCGTAGATGCCCTGGCCCAGGG
  CCCTGACTCCTCCATTCCCGCCAGTAGCTGTTCCTAGTGTATTTTCGTCTTTCTGGAAAA
  CAGCATTGAGTGGTTGTTTTCTGTGTAAAGAGCCGTTTGTGTCTTGGGAGTTTGTGGCCC
  ACATGCCGATAGCACGGTCATCGCACATGACTCTCCCGTTTGTCTCAGTGTCCCTGCAAC
  AAGCAGCACCGCAGACTGTAATAAAAGGTGGGGTTTTGTGAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_052821
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_052821.3, NP_438172.1
• RefSeq Size: 3078 bp
• RefSeq ORF: 1005 bp
• Locus ID: 11091
• UniProt ID: P61964
• Cytogenetics: 9q34.2
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. The two variants encode the same protein.