LILRB3 (NM_001081450) Human Untagged Clone

CAT#: SC315965

LILRB3 (untagged)-Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 (LILRB3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LILRB3
• Synonyms: CD85A; HL9; ILT-5; ILT5; LILRA6; LIR-3; LIR3; PIR-B; PIRB
• Vector: PCMV6-Neo
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001081450 edited
  ATGACGCCCGCCCTCACAGCCCTGCTCTGCCTTGGGCTGAGTCTGGGCCCCAGGACCCGC
  GTGCAGGCAGGGCCCTTCCCCAAACCCACCCTCTGGGCTGAGCCAGGCTCTGTGATCAGC
  TGGGGGAGCCCCGTGACCATCTGGTGTCAGGGGAGCCAGGAGGCCCAGGAGTACCGACTG
  CATAAAGAGGGAAGCCCAGAGCCCTTGGACAGAAATAACCCACTGGAACCCAAGAACAAG
  GCCAGATTCTCCATCCCATCCATGACAGAGCACCATGCAGGGAGATACCGCTGCCACTAT
  TACAGCTCTGCAGGCTGGTCAGAGCCCAGCGACCCCCTGGAGATGGTGATGACAGGAGCC
  TACAGCAAACCCACCCTCTCAGCCCTGCCCAGCCCTGTGGTGGCCTCAGGGGGGAATATG
  ACCCTCCGATGTGGCTCACAGAAGGGATATCACCATTTTGTTCTGATGAAGGAAGGAGAA
  CACCAGCTCCCCCGGACCCTGGACTCACAGCAGCTCCACAGTCGGGGGTTCCAGGCCCTG
  TTCCCTGTGGGCCCCGTGACCCCCAGCCACAGGTGGAGGTTCACATGCTATTACTATTAT
  ACAAACACCCCCTGGGTGTGGTCCCACCCCAGTGACCCCCTGGAGATTCTGCCCTCAGGC
  GTGTCTAGGAAGCCCTCCCTCCTGACCCTGCAGGGCCCTGTCCTGGCCCCTGGGCAGAGC
  CTGACCCTCCAGTGTGGCTCTGATGTCGGCTACAACAGATTTGTTCTGTATAAGGAGGGG
  GAACGTGACTTCCTCCAGCGCCCTGGCCAGCAGCCCCAGGCTGGGCTCTCCCAGGCCAAC
  TTCACCCTGGGCCCTGTGAGCCCCTCCAATGGGGGCCAGTACAGGTGCTACGGTGCACAC
  AACCTCTCCTCCGAGTGGTCGGCCCCCAGCGACCCCCTGAACATCCTGATGGCAGGACAG
  ATCTATGACACCGTCTCCCTGTCAGCACAGCCGGGCCCCACAGTGGCCTCAGGAGAGAAC
  GTGACCCTGCTGTGTCAGTCATGGTGGCAGTTTGACACTTTCCTTCTGACCAAAGAAGGG
  GCAGCCCATCCCCCACTGCGTCTGAGATCAATGTACGGAGCTCATAAGTACCAGGCTGAA
  TTCCCCATGAGTCCTGTGACCTCAGCCCACGCGGGGACCTACAGGTGCTACGGCTCATAC
  AGCTCCAACCCCCACCTGCTGTCTCACCCCAGTGAGCCCCTGGAGCTCGTGGTCTCAGGA
  CACTCTGGAGGCTCCAGCCTCCCACCCACAGGGCCGCCCTCCACACCTGGTCTGGGAAGA
  TACCTGGAGGTTTTGATTGGGGTCTCGGTGGCCTTCGTCCTGCTGCTCTTCCTCCTCCTC
  TTCCTCCTCCTCCGACGTCAGCGTCACAGCAAACACAGGACATCTGACCAGAGAAAGACT
  GATTTCCAGCGTCCTGCAGGGGCTGCGGAGACAGAGCCCAAGGACAGGGGCCTGCTGAGG
  AGGTCCAGCCCAGCTGCTGACGTCCAGGAAGAAAACCTCTATGCTGCCGTGAAGGACACA
  CAGTCTGAGGACAGGGTGGAGCTGGACAGTCAGCAGAGCCCACACGATGAAGACCCCCAG
  GCAGTGACGTATGCCCCGGTGAAACACTCCAGTCCTAGGAGAGAAATGGCCTCTCCTCCC
  TCCTCACTGTCTGGGGAATTCCTGGACACAAAGGACAGACAGGTGGAAGAGGACAGGCAG
  ATGGACACTGAGGCTGCTGCATCTGAAGCCTCCCAGGATGTGACCTACGCCCAGCTGCAC
  AGCTTGACCCTTAGACGGAAGGCAACTGAGCCTCCTCCATCCCAGGAAGGGGAACCTCCA
  GCTGAGCCCAGCATCTACGCCACTCTGGCCATCCACTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001081450
• Insert Size: 1900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001081450.1, NP_001074919.1
• RefSeq Size: 2843 bp
• RefSeq ORF: 1899 bp
• Locus ID: 11025
• Cytogenetics: 19q13.42
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: B cell receptor signaling pathway
• Gene Summary: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).