CACNA1G (NM_198382) Human Untagged Clone

CAT#: SC307676

CACNA1G (untagged)-Human calcium channel, voltage-dependent, T type, alpha 1G subunit (CACNA1G), transcript variant 11

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CACNA1G
• Synonyms: Ca(V)T.1; Cav3.1; NBR13; SCA42; SCA42ND
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_198382 edited
  CCGCCCTCCGCCGCTGCCCCCCTTTTCGTTCGCCCTCTCGGGGCGGCTTCGCCGAAGGTA
  GCGCCGAATCCGGCAACCGGAGCCTGGGCGCGAAGCGAAGAAGCCGGAACAAAGTGAGGG
  GGAGCCGGCCGGCTGGCCCGGGAAGCCCCAGGGGCGCAGGGGAAGCGGGACTCGCGCCGG
  GCGGGGTTTCCCTGCGCCCCGGCGCCCCGCGGGCAGCATGCCCCTGCGGGCAGGGGGAGC
  TGGGCTGAACTGGCCCTCCCGGGGGCTCAGCTTGCGCCCTAGAGCCCACCAGATGTGCCC
  CCGCCGGGGCCCCCGGGTTGCGTGAGGACACCTCCTCTGAGGGGCGCCGCTTGCCCCTCT
  CCGGATCGCCCGGGGCCCCGGCTGGCCAGAGGATGGACGAGGAGGAGGATGGAGCGGGCG
  CCGAGGAGTCGGGACAGCCCCGGAGCTTCATGCGGCTCAACGACCTGTCGGGGGCCGGGG
  GCCGGCCGGGGCCGGGGTCAGCAGAAAAGGACCCGGGCAGCGCGGACTCCGAGGCGGAGG
  GGCTGCCGTACCCGGCGCTGGCCCCGGTGGTTTTCTTCTACTTGAGCCAGGACAGCCGCC
  CGCGGAGCTGGTGTCTCCGCACGGTCTGTAACCCCTGGTTTGAGCGCATCAGCATGTTGG
  TCATCCTTCTCAACTGCGTGACCCTGGGCATGTTCCGGCCATGCGAGGACATCGCCTGTG
  ACTCCCAGCGCTGCCGGATCCTGCAGGCCTTTGATGACTTCATCTTTGCCTTCTTTGCCG
  TGGAGATGGTGGTGAAGATGGTGGCCTTGGGCATCTTTGGGAAAAAGTGTTACCTGGGAG
  ACACTTGGAACCGGCTTGACTTTTTCATCGTCATCGCAGGGATGCTGGAGTACTCGCTGG
  ACCTGCAGAACGTCAGCTTCTCAGCTGTCAGGACAGTCCGTGTGCTGCGACCGCTCAGGG
  CCATTAACCGGGTGCCCAGCATGCGCATCCTTGTCACGTTGCTGCTGGATACGCTGCCCA
  TGCTGGGCAACGTCCTGCTGCTCTGCTTCTTCGTCTTCTTCATCTTCGGCATCGTCGGCG
  TCCAGCTGTGGGCAGGGCTGCTTCGGAACCGATGCTTCCTACCTGAGAATTTCAGCCTCC
  CCCTGAGCGTGGACCTGGAGCGCTATTACCAGACAGAGAACGAGGATGAGAGCCCCTTCA
  TCTGCTCCCAGCCACGCGAGAACGGCATGCGGTCCTGCAGAAGCGTGCCCACGCTGCGCG
  GGGACGGGGGCGGTGGCCCACCTTGCGGTCTGGACTATGAGGCCTACAACAGCTCCAGCA
  ACACCACCTGTGTCAACTGGAACCAGTACTACACCAACTGCTCAGCGGGGGAGCACAACC
  CCTTCAAGGGCGCCATCAACTTTGACAACATTGGCTATGCCTGGATCGCCATCTTCCAGG
  TCATCACGCTGGAGGGCTGGGTCGACATCATGTACTTTGTGATGGATGCTCATTCCTTCT
  ACAATTTCATCTACTTCATCCTCCTCATCATCGTGGGCTCCTTCTTCATGATCAACCTGT
  GCCTGGTGGTGATTGCCACGCAGTTCTCAGAGACCAAGCAGCGGGAAAGCCAGCTGATGC
  GGGAGCAGCGTGTGCGGTTCCTGTCCAACGCCAGCACCCTGGCTAGCTTCTCTGAGCCCG
  GCAGCTGCTATGAGGAGCTGCTCAAGTACCTGGTGTACATCCTTCGTAAGGCAGCCCGCA
  GGCTGGCTCAGGTCTCTCGGGCAGCAGGTGTGCGGGTTGGGCTGCTCAGCAGCCCAGCAC
  CCCTCGGGGGCCAGGAGACCCAGCCCAGCAGCAGCTGCTCTCGCTCCCACCGCCGCCTAT
  CCGTCCACCACCTGGTGCACCACCACCACCACCATCACCACCACTACCACCTGGGCAATG
  GGACGCTCAGGGCCCCCCGGGCCAGCCCGGAGATCCAGGACAGGGATGCCAATGGGTCCC
  GCAGGCTCATGCTGCCACCACCCTCGACGCCTGCCCTCTCCGGGGCCCCCCCTGGTGGCG
  CAGAGTCTGTGCACAGCTTCTACCATGCCGACTGCCACTTAGAGCCAGTCCGCTGCCAGG
  CGCCCCCTCCCAGGTCCCCATCTGAGGCATCCGGCAGGACTGTGGGCAGCGGGAAGGTGT
  ATCCCACCGTGCACACCAGCCCTCCACCGGAGACGCTGAAGGAGAAGGCACTAGTAGAGG
  TGGCTGCCAGCTCTGGGCCCCCAACCCTCACCAGCCTCAACATCCCACCCGGGCCCTACA
  GCTCCATGCACAAGCTGCTGGAGACACAGAGTACAGGTGCCTGCCAAAGCTCTTGCAAGA
  TCTCCAGCCCTTGCTTGAAAGCAGACAGTGGAGCCTGTGGTCCAGACAGCTGCCCCTACT
  GTGCCCGGGCCGGGGCAGGGGAGGTGGAGCTCGCCGACCGTGAAATGCCTGACTCAGACA
  GCGAGGCAGTTTATGAGTTCACACAGGATGCCCAGCACAGCGACCTCCGGGACCCCCACA
  GCCGGCGGCAACGGAGCCTGGGCCCAGATGCAGAGCCCAGCTCTGTGCTGGCCTTCTGGA
  GGCTAATCTGTGACACCTTCCGAAAGATTGTGGACAGCAAGTACTTTGGCCGGGGAATCA
  TGATCGCCATCCTGGTCAACACACTCAGCATGGGCATCGAATACCACGAGCAGCCCGAGG
  AGCTTACCAACGCCCTAGAAATCAGCAACATCGTCTTCACCAGCCTCTTTGCCCTGGAGA
  TGCTGCTGAAGCTGCTTGTGTATGGTCCCTTTGGCTACATCAAGAATCCCTACAACATCT
  TCGATGGTGTCATTGTGGTCATCAGCGTGTGGGAGATCGTGGGCCAGCAGGGGGGCGGCC
  TGTCGGTGCTGCGGACCTTCCGCCTGATGCGTGTGCTGAAGCTGGTGCGCTTCCTGCCGG
  CGCTGCAGCGGCAGCTGGTGGTGCTCATGAAGACCATGGACAACGTGGCCACCTTCTGCA
  TGCTGCTTATGCTCTTCATCTTCATCTTCAGCATCCTGGGCATGCATCTCTTCGGCTGCA
  AGTTTGCCTCTGAGCGGGATGGGGACACCCTGCCAGACCGGAAGAATTTTGACTCCTTGC
  TCTGGGCCATCGTCACTGTCTTTCAGATCCTGACCCAGGAGGACTGGAACAAAGTCCTCT
  ACAATGGTATGGCCTCCACGTCGTCCTGGGCGGCCCTTTATTTCATTGCCCTCATGACCT
  TCGGCAACTACGTGCTCTTCAATTTGCTGGTCGCCATTCTGGTGGAGGGCTTCCAGGCGG
  AGGGAGATGCCAACAAGTCCGAATCAGAGCCCGATTTCTTCTCACCCAGCCTGGATGGTG
  ATGGGGACAGGAAGAAGTGCTTGGCCTTGGTGTCCCTGGGAGAGCACCCGGAGCTGCGGA
  AGAGCCTGCTGCCGCCTCTCATCATCCACACGGCCGCCACACCCATGTCGCTGCCCAAGA
  GCACCAGCACGGGCCTGGGCGAGGCGCTGGGCCCTGCGTCGCGCCGCACCAGCAGCAGCG
  GGTCGGCAGAGCCTGGGGCGGCCCACGAGATGAAGTCACCGCCCAGCGCCCGCAGCTCTC
  CGCACAGCCCCTGGAGCGCTGCAAGCAGCTGGACCAGCAGGCGCTCCAGCCGGAACAGCC
  TCGGCCGTGCACCCAGCCTGAAGCGGAGAAGCCCAAGTGGAGAGCGGCGGTCCCTGTTGT
  CGGGAGAAGGCCAGGAGAGCCAGGATGAAGAGGAGAGCTCAGAAGAGGAGCGGGCCAGCC
  CTGCGGGCAGTGACCATCGCCACAGGGGGTCCCTGGAGCGGGAGGCCAAGAGTTCCTTTG
  ACCTGCCAGACACACTGCAGGTGCCAGGGCTGCATCGCACTGCCAGTGGCCGAGGGTCTG
  CTTCTGAGCACCAGGACTGCAATGGCAAGTCGGCTTCAGGGCGCCTGGCCCGGGCCCTGC
  GGCCTGATGACCCCCCACTGGATGGGGATGACGCCGATGACGAGGGCAACCTGAGCAAAG
  GGGAACGGGTCCGCGCGTGGATCCGAGCCCGACTCCCTGCCTGCTGCCTCGAGCGAGACT
  CCTGGTCAGCCTACATCTTCCCTCCTCAGTCCAGGTTCCGCCTCCTGTGTCACCGGATCA
  TCACCCACAAGATGTTCGACCACGTGGTCCTTGTCATCATCTTCCTTAACTGCATCACCA
  TCGCCATGGAGCGCCCCAAAATTGACCCCCACAGCGCTGAACGCATCTTCCTGACCCTCT
  CCAATTACATCTTCACCGCAGTCTTTCTGGCTGAAATGACAGTGAAGGTGGTGGCACTGG
  GCTGGTGCTTCGGGGAGCAGGCGTACCTGCGGAGCAGTTGGAACGTGCTGGACGGGCTGT
  TGGTGCTCATCTCCGTCATCGACATTCTGGTGTCCATGGTCTCTGACAGCGGCACCAAGA
  TCCTGGGCATGCTGAGGGTGCTGCGGCTGCTGCGGACCCTGCGCCCGCTCAGGGTGATCA
  GCCGGGCGCAGGGGCTGAAGCTGGTGGTGGAGACGCTGATGTCCTCACTGAAACCCATCG
  GCAACATTGTAGTCATCTGCTGTGCCTTCTTCATCATTTTCGGCATCTTGGGGGTGCAGC
  TCTTCAAAGGGAAGTTTTTCGTGTGCCAGGGCGAGGATACCAGGAACATCACCAATAAAT
  CGGACTGTGCCGAGGCCAGTTACCGGTGGGTCCGGCACAAGTACAACTTTGACAACCTTG
  GCCAGGCCCTGATGTCCCTGTTCGTTTTGGCCTCCAAGGATGGTTGGGTGGACATCATGT
  ACGATGGGCTGGATGCTGTGGGCGTGGACCAGCAGCCCATCATGAACCACAACCCCTGGA
  TGCTGCTGTACTTCATCTCGTTCCTGCTCATTGTGGCCTTCTTTGTCCTGAACATGTTTG
  TGGGTGTGGTGGTGGAGAACTTCCACAAGTGTCGGCAGCACCAGGAGGAAGAGGAGGCCC
  GGCGGCGGGAGGAGAAGCGCCTACGAAGACTGGAGAAAAAGAGAAGGAATCTAATGCTGG
  ACGATGTAATTGCTTCCGGCAGCTCAGCCAGCGCTGCGTCAGAAGCCCAGTGCAAACCTT
  ACTACTCCGACTACTCCCGCTTCCGGCTCCTCGTCCACCACTTGTGCACCAGCCACTACC
  TGGACCTCTTCATCACAGGTGTCATCGGGCTGAACGTGGTCACCATGGCCATGGAGCACT
  ACCAGCAGCCCCAGATTCTGGATGAGGCTCTGAAGATCTGCAACTACATCTTCACTGTCA
  TCTTTGTCTTGGAGTCAGTTTTCAAACTTGTGGCCTTTGGTTTCCGTCGGTTCTTCCAGG
  ACAGGTGGAACCAGCTGGACCTGGCCATTGTGCTGCTGTCCATCATGGGCATCACGCTGG
  AGGAAATCGAGGTCAACGCCTCGCTGCCCATCAACCCCACCATCATCCGCATCATGAGGG
  TGCTGCGCATTGCCCGAGTGCTGAAGCTGCTGAAGATGGCTGTGGGCATGCGGGCGCTGC
  TGGACACGGTGATGCAGGCCCTGCCCCAGGTGGGGAACCTGGGACTTCTCTTCATGTTGT
  TGTTTTTCATCTTTGCAGCTCTGGGCGTGGAGCTCTTTGGAGACCTGGAGTGTGACGAGA
  CACACCCCTGTGAGGGCCTGGGCCGTCATGCCACCTTTCGGAACTTTGGCATGGCCTTCC
  TAACCCTCTTCCGAGTCTCCACAGGTGACAATTGGAATGGCATTATGAAGGACACCCTCC
  GGGACTGTGACCAGGAGTCCACCTGCTACAACACGGTCATCTCGCCTATCTACTTTGTGT
  CCTTCGTGCTGACGGCCCAGTTCGTGCTAGTCAACGTGGTGATCGCCGTGCTGATGAAGC
  ACCTGGAGGAGAGCAACAAGGAGGCCAAGGAGGAGGCCGAGCTAGAGGCTGAGCTGGAGC
  TGGAGATGAAGACCCTCAGCCCCCAGCCCCACTCGCCACTGGGCAGCCCCTTCCTCTGGC
  CTGGGGTCGAGGGCCCCGACAGCCCCGACAGCCCCAAGCCTGGGGCTCTGCACCCAGCGG
  CCCACGCGAGATCAGCCTCCCACTTTTCCCTGGAGCACCCCACGATGCAGCCCCACCCCA
  CGGAGCTGCCAGGACCAGACTTACTGACTGTGCGGAAGTCTGGGGTCAGCCGAACGCACT
  CTCTGCCCAATGACAGCTACATGTGTCGGCATGGGAGCACTGCCGAGGGGCCCCTGGGAC
  ACAGGGGCTGGGGGCTCCCCAAAGCTCAGTCAGGCTCCGTCTTGTCCGTTCACTCCCAGC
  CAGCAGATACCAGCTACATCCTGCAGCTTCCCAAAGATGCACCTCATCTGCTCCAGCCCC
  ACAGCGCCCCAACCTGGGGCACCATCCCCAAACTGCCCCCACCAGGACGCTCCCCTTTGG
  CTCAGAGGCCACTCAGGCGCCAGGCAGCAATAAGGACTGACTCCTTGGACGTTCAGGGTC
  TGGGCAGCCGGGAAGACCTGCTGGCAGAGGTGAGTGGGCCCTCCCCGCCCCTGGCCCGGG
  CCTACTCTTTCTGGGGCCAGTCAAGTACCCAGGCACAGCAGCACTCCCGCAGCCACAGCA
  AGATCTCCAAGCACATGACCCCGCCAGCCCCTTGCCCAGGCCCAGAACCCAACTGGGGCA
  AGGGCCCTCCAGAGACCAGAAGCAGCTTAGAGTTGGACACGGAGCTGAGCTGGATTTCAG
  GAGACCTCCTGCCCCCTGGCGGCCAGGAGGAGCCCCCATCCCCACGGGACCTGAAGAAGT
  GCTACAGCGTGGAGGCCCAGAGCTGCCAGCGCCGGCCTACGTCCTGGCTGGATGAGCAGA
  GGAGACACTCTATCGCCGTCAGCTGCCTGGACAGCGGCTCCCAACCCCACCTGGGCACAG
  ACCCCTCTAACCTTGGGGGCCAGCCTCTTGGGGGGCCTGGGAGCCGGCCCAAGAAAAAAC
  TCAGCCCGCCTAGTATCACCATAGACCCCCCCGAGAGCCAAGGTCCTCGGACCCCGCCCA
  GCCCTGGTATCTGCCTCCGGAGGAGGGCTCCGTCCAGCGACTCCAAGGATCCCTTGGCCT
  CTGGCCCCCCTGACAGCATGGCTGCCTCGCCCTCCCCAAAGAAAGATGTGCTGAGTCTCT
  CCGGTTTATCCTCTGACCCAGCAGACCTGGACCCCTGAGTCCTGCCCCACTTTCCCACTC
  ACCTTTCTCCACTGGGTGCCAAGTCCTAGCTCCTCCTCCTGGGCTATATTCCTGACAAAA
  GTTCCATATAGACACCAAGGAGGCGGAGGCGCTCCTCCCTGCCTCAGTGGCTCTGGGTAC
  CTGCAAGCAGAACTTCCAAAGAGAGTTAAAAGCAGCAGCCCCGGCAACTCTGGCTCCAGG
  CAGAAGGAGAGGCCCGGTGCAGCTGAGGTTCCCGACACCAGAAGCTGTTGGGAGAAAGCA
  ATACGTTTGTGCAGAATCTCTATGTATATTCTATTTTATTAAATTAATTGAATCTAGAAA
  AAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_198382
• Insert Size: 7500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain one SNP compared with NM_198382.1.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_198382.1, NP_938196.1
• RefSeq Size: 7477 bp
• RefSeq ORF: 6786 bp
• Locus ID: 8913
• UniProt ID: O43497
• Cytogenetics: 17q21.33
• Protein Families: Druggable Genome, Ion Channels: Calcium, Transmembrane
• Protein Pathways: Calcium signaling pathway, MAPK signaling pathway, Type II diabetes mellitus
• Gene Summary: Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011]
  Transcript Variant: This variant (11) lacks three exons in the coding region, compared to variant 1. The resulting isoform (11) lacks a segment in the central region and a segment in the C-terminal region, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.