BMP8A (NM_181809) Human Untagged Clone

CAT#: SC307379

BMP8A (untagged)-Human bone morphogenetic protein 8a (BMP8A)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BMP8A
• Synonyms: OP-2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_181809 edited
  ATGGCCGCGCGCCCCGGACCGCTCTGGCTTCTGGGCCTGACGTTGTGCGCGCTGGGCGGG
  GGCGGCCCCGGCCTGCGACCCCCGCCCGGCTGTCCCCAGCGACGTCTGGGCGCGCGCGAG
  CGCCGGGACGTGCAGCGCGAGATCCTGGCGGTGCTCGGGCTACCCGGGCGGCCCCGGCCC
  CGCGCGCCACCCGCCGCCTCCCGGCTGCCCGCGTCCGCGCCGCTCTTCATGCTGGACCTG
  TACCACGCCGTGGCTGGCGACGACGACGAGGACGGCGCGCCCGCGGAGCAGCGCCTGGGC
  CGCGCCGACCTGGTCATGAGCTTCGTCAACATGGTGGAGCGAGACCGTGCCCTGGGCCAC
  CAGGAGCCCCATTGGAAGGAGTTCCGCTTTGACCTGACCCAGATCCCGGCTGGGGAGGCG
  GTCACAGCTGCGGAGTTCCGGATTTACAAGGTGCCCAGCATCCACCTGCTCAACAGGACC
  CTCCACGTCAGCATGTTCCAGGTGGTCCAGGAGCAGTCCAACAGGGAGTCTGACTTGTTC
  TTTTTGGATCTTCAGACGCTCCGAGCTGGAGACGAGGGCTGGCTGGTGCTGGATGTCACA
  GCAGCCAGTGACTGCTGGTTGCTGAAGCGTCACAAGGACCTGGGACTCCGCCTCTATGTG
  GAGACTGAGGATGGGCACAGCGTGGATCCTGGCCTGGCCGGCCTGCTGGGTCAACGGGCC
  CCACGCTCCCAACAGCCTTTCGTGGTCACTTTCTTCAGGGCCAGTCCGAGTCCCATCCGC
  ACCCCTCGGGCAGTGAGGCCACTGAGGAGGAGGCAGCCGAAGAAAACCAACGAGCTGCCG
  CAGGCCAACCGACTCCCAGGGATCTTTGATGACGTCCACGGCTCCCACGGCCGGCAGGTC
  TGCCGTCGGCACGAGCTCTACGTCAGCTTCCAGGACCTTGGCTGGCTGGACTGGGTCATC
  GCCCCCCAAGGCTACTCAGCCTATTACTGTGAGGGGGAGTGCTCCTTCCCGCTGGACTCC
  TGCATGAACGCCACCAACCACGCCATCCTGCAGTCCCTGGTGCACCTGATGAAGCCAAAC
  GCAGTCCCCAAGGCGTGCTGTGCACCCACCAAGCTGAGCGCCACCTCTGTGCTCTACTAT
  GACAGCAGCAACAACGTCATCCTGCGCAAGCACCGCAACATGGTGGTCAAGGCCTGCGGC
  TGCCACTGAGTCAGCCCGCCCAGCCCTACTGCAGCCACCCTTCTCATCTGGATCGGGCCC
  TGCAGAGGCAGAAAACCCTTAAATGCTGTCACAGCTCAAGCAGGAGTGTCAGGGGCCCTC
  ACTCTCGGTGCCTACTTCCTGTCAGGCTTCTGGTCCTTTCTCGGTACCTCTGTGCCCCTC
  CCCTGGGGTTTGTGGCTGTCACTCTGCCCGACACTTTGGTGGCCTAAGGCACACAGCAGC
  CTCAGAGCCTGTGCTGACTGCACTGTCTGGAGTGAGTCAGCACAGAAGTCCTATCTTAGG
  ACCTGTCAGACTGTGGCTGGCCCCGGATGGTCTGAGGTTGGCTGACCCGAGCTTTTCTCC
  ATTCACCAGAGGGTTTAGGTGTGAGGAGAAGGGCTCTGCCTCTTCCCAGGTACAACACTG
  GCCATTTCTGGGCAAAATTGGACACGCTTATGTTCTCAGCACAGTGTGTTCTGGGATTCT
  TCTCATTTGGTCCAGGGTGCAGTTAGCATATTAGAAAAAGAATAAGCTGGACATCCCCCC
  GGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_181809 unedited
  GGTTCTTATTTGTATACGACTTATATAGGCGGCCGCGATTCTGGCCGCGCGCCCCGGACC
  GCTCTGGCTTCTGGGCCTGACGTTGTGCGCGCTGGGCGGGGGCGGCCCCGGCCTGCGACC
  CCCGCCCGGCTGTCCCCAGCGACGTCTGGGCGCGCGCGAGCGCCGGGACGTGCAGCGCGA
  GATCCTGGCGGTGCTCGGGCTACCCGGGCGGCCCCGGCCCCGCGCGCCACCCGCCGCCTC
  CCGGCTGCCCGCGTCCGCGCCGCTCTTCATGCTGGACCTGTACCACGCCGTGGCTGGCGA
  CGACGACGAGGACGGCGCGCCCGCGGAGCAGCGCCTGGGCCGCGCCGACCTGGTCATGAG
  CTTCGTCAACATGGTGGAGCGAGACCGTGCCCTGGGCCACCAGGAGCCCCATTGGAAGGA
  GTTCCGCTTTGACCTGACCCAGATCCCGGCTGGGGAGGCGGTCACAGCTGCGGAGTTCCG
  GATTTACAAGGTGCCCAGCATCCACCTGCTCAACAGGACCCTCCACGTCAGCATGTTCCA
  GGTGGTCCAGGAGCAGTCCAACAGGGAGTCTGACTTGTTCTTTTTGGATCTTCAGACGCT
  CCGAGCTGGAGACGAGGGCTGGCTGGTGCTGGATGTCACAGCAGCCAGTGACTGCTGGTT
  GCTGAAGCGTCACAAGGACCTGGGACTCCGCCTCTATGTGGAGACTGANGATGGGCACAG
  CGTGGATCCTGGCCTGGCCGGCCTGCTGGGTCAACGGGCCCCACGCTCCCACAGCCTTTC
  GTGGTCACTTTCTTCAGGGCCAGTCCGAGTCCCATCCGCACCCCTCGGGGCAGTGAGCCA
  CTGAGGAGGAGGGCAGCCGAGAAAAACAACGAGCTGCCGCAGGCCAACCCGACTCCAGGG
  ATCTTTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_181809 unedited
  GNANGAGCACTGGGGNAGGGTCACAGGGATGCCACCCGGGCTCTGTTCAGGAAACAGCTA
  TGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTCGGGGGGATGTCCAGCTTATTCTTTTTCTAATATGCTAACT
  GCCCCCTGGACCAAATGAGAAAAATCCCAAAACACACTGTGCTGAAAACATAAGCGTGTC
  CAATTTTGCCCAAAAATGGCCAGTGTTGTCCCTGGGAAAAGGCAAAGCCCTTTTCCTCAC
  ACCTAAACCCTTTGGTGAATGGAAAAAAGCTCGGGTCAGCCAACCTCAAACCATCCGGGG
  CCAGCCACAGTCTGACAGGTCCTAAAATAGGACTTCTGTGCTGACTCACTCCAAACAGTG
  CAGTCAGCACAGGCTCTGAGGCTGCTGTGTGCCTTAGGCCACCAAAGTGTCGGGCAAAGT
  GACAGCCACAAACCCCAGGGGAGGGGCACAGAGGTCCCGAGAAAGGACCAAAACCCTGAC
  AGGAAGTAGGCCCCGAGAGTGAGGGCCCCTGACACTCCTGCTTGAGCTGTGACAGCATTT
  AAGGGTTTTCTGCCTCTGCAGGGCCCGATCCAAATGAGAAGGGTGGCTGCATTAGGGCTG
  GGCGGGCTGACTCAGTGGCAGCCGCAGGCCTTGACCACCATGTTGCGGTGCTTGCGCAGG
  ATGACCTTGTTGCTGCTGTCATAATAGAGCACAGAGGTGGCGCTCAACTTGGTGGGTGCA
  CAGCACGCCTTGGGGACTGCGTTTGGCTTCTCAAGTCCACAAGGACTGCAGGATGGCTTG
  GTTGGTGGCCTNCATGCAAGAATCCAGCG
  
• Restriction Sites: Please inquire
• ACCN: NM_181809
• Insert Size: 1800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_181809.1, NP_861525.1
• RefSeq Size: 1692 bp
• RefSeq ORF: 1209 bp
• Locus ID: 353500
• UniProt ID: Q7Z5Y6
• Cytogenetics: 1p34.3
• Protein Families: Secreted Protein
• Protein Pathways: Hedgehog signaling pathway, TGF-beta signaling pathway
• Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]