Eotaxin 3 (CCL26) (NM_006072) Human Untagged Clone

CAT#: SC303732

CCL26 (untagged)-Human chemokine (C-C motif) ligand 26 (CCL26)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Eotaxin 3
• Synonyms: IMAC; MIP-4a; MIP-4alpha; SCYA26; TSC-1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006072 edited
  CAGGCAGGAGGAGTTTGGGAGAAACCTGAGAAGGGCCTGATTTGCAGCATCATGATGGGC
  CTCTCCTTGGCCTCTGCTGTGCTCCTGGCCTCCCTCCTGAGTCTCCACCTTGGAACTGCC
  ACACGTGGGAGTGACATATCCAAGACCTGCTGCTTCCAATACAGCCACAAGCCCCTTCCC
  TGGACCTGGGTGCGAAGCTATGAATTCACCAGTAACAGCTGCTCCCAGCGGGCTGTGATA
  TTCACTACCAAAAGAGGCAAGAAAGTCTGTACCCATCCAAGGAAAAAATGGGTGCAAAAA
  TACATTTCTTTACTGAAAACTCCGAAACAATTGTGACTCAGCTGAATTGTCATCCGAGGA
  CGCTTGGACCCCGCTCTTGGCTCTGC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006072 unedited
  NGGAAGGTCAGATTTGTTTACGACTTATATAGGCGGCCGCGCATTCANATCTGGTACCGG
  GCCCCCCCNTCGGGTCGACGGTATCGATAAGCTTGATATCGAATTCCTGCAGCCCGGGGG
  ATCCGCCCAGGCAGGAGGAGTTTGGGAGAAACCTGAGAAGGGCCTGATTTGCAGCATCAT
  GATGGGCCTCTCCTTGGCCTCTGCTGTGCTCCTGGCCTCCCTCCTGAGTCTCCACCTTGG
  AACTGCCACACGTGGGAGTGACATATCCAAGACCTGCTGCTTCCAATACAGCCACAAGCC
  CCTTCCCTGGACCTGGGTGCGAAGCTATGAATTCACCAGTAACAGCTGCTCCCAGCGGGC
  TGTGATATTCACTACCAAAAGAGGCAAGAAAGTCTGTACCCATCCAAGGAAAAAATGGGT
  GCAAAAATACATTTCTTTACTGAAAACTCCGAAACAATTGTGACTCAGCTGAATTGTCAT
  CCGAGGACGCTTGGACCCCGCTCTTGGCTCTGCGGGCTAGAGCGGCCGCGGTCATAGCTG
  TTTCCTGAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCC
  TGGAAGTTGCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATAAGTTGCATCATTTT
  GTCTGACTAGGTGTCCTTCTATAATATTATGGNGTGGAAGGGGGTGGTATGGAGCAAGGG
  CAAGTTGGGAAAACAACCTGTTAGGCCTGCGGGGTCTATTGGGAACCCAAGCTGAGTGCA
  GTGGCCCAATCTTGGCTCACTGCAATCTCCGCCTCCTGGGTTCAAGCGATTCTCCTGGCT
  TAACCTTCCCGATTTGTTGGGATTCCGGCCTGCCTGGACCGGGTTAAGTTAATTTTGGTT
  TTTTG
  
• Restriction Sites: Please inquire
• ACCN: NM_006072
• Insert Size: 400 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006072.4, NP_006063.1
• RefSeq Size: 562 bp
• RefSeq ORF: 285 bp
• Locus ID: 10344
• UniProt ID: Q9Y258
• Cytogenetics: 7q11.23
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction
• Gene Summary: This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. This protein also has antimicrobial activity, displaying an antibacterial effect on S. pneumoniae, S. aureus, Non-typeable H. influenzae, and P. aeruginosa. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2020]