CDKN3 (NM_005192) Human Untagged Clone

CAT#: SC127857

CDKN3 (untagged)-Human cyclin-dependent kinase inhibitor 3 (CDKN3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDKN3
• Synonyms: CDI1; CIP2; KAP; KAP1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005192, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAGCCGCCCAGTTCAATACAAACAAGTGAGTTTGACTCATCAGATGAAGAGCCTATTGAAGATGAAC
  AGACTCCAATTCATATATCATGGCTATCTTTGTCACGAGTGAATTGTTCTCAGTTTCTCGGTTTATGTGC
  TCTTCCAGGTTGTAAATTTAAAGATGTTAGAAGAAATGTCCAAAAAGATACAGAAGAACTAAAGAGCTGT
  GGTATACAAGACATATTTGTTTTCTGCACCAGAGGGGAACTGTCAAAATATAGAGTCCCAAACCTTCTGG
  ATCTCTACCAGCAATGTGGAATTATCACCCATCATCATCCAATCGCAGATGGAGGGACTCCTGACATAGC
  CAGCTGCTGTGAAATAATGGAAGAGCTTACAACCTGCCTTAAAAATTACCGAAAAACCTTAATACACTGC
  TATGGAGGACTTGGGAGATCTTGTCTTGTAGCTGCTTGTCTCCTACTATACCTGTCTGACACAATATCAC
  CAGAGCAAGCCATAGACAGCCTGCGAGACCTAAGAGGATCCGGGGCAATACAGACCATCAAGCAATACAA
  TTATCTTCATGAGTTTCGGGACAAATTAGCTGCACATCTATCATCAAGAGATTCACAATCAAGATCTGTA
  TCAAGATAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005192 unedited
  ACGACTCCTATAGGGCGGCCGCGAATTCGGCACCAGGGGGCGCGGGCTCGGCCGGGGCAC
  CGGTGAGTCGCCGGCGCTGCAGAGGGAGGCGGCACTGGTCTCGACGTGGGGCGGCCAGCG
  ATGAAGCCGCCCAGTTCAATACAAACAAGTGAGTTTGACTCATCAGATGAAGAGCCTATT
  GAAGATGAACAGACTCCAATTCATATATCATGGCTATCTTTGTCACGAGTGAATTGTTCT
  CAGTTTCTCGGTTTATGTGCTCTTCCAGGTTGTAAATTTAAAGATGTTAGAAGAAATGTC
  CAAAAAGATACAGAAGAACTAAAGAGCTGTGGTATACAAGACATATTTGTTTTCTGCACC
  AGAGGGGAACTGTCAAAATATAGAGTCCCAAACCTTCTGGATCTCTACCAGCAATGTGGA
  ATTATCACCCATCATCATCCAATCGCAGATGGAGGGACTCCTGACATAGCCAGCTGCTGT
  GAAATAATGGAAGAGCTTACAACCTGCCTTAAAAATNTACCGAAAACCTTAATACACTGC
  TATGGAGGACTTGGGAGATCTTGTCTTGTAGCTGCTTGTCTCCTACTATACCTGTCTGAC
  ACAATATCACCAGAGCAAGCCATAGACAGCCTGCGAGACCTAAGAGGATCCGGGGCAATA
  CAGACCATCAAGCAATACAATTATCTTCATGAGTTTCGGGACAAATAGCTGCCATCTATC
  ATCAAGAGATCACATTCAAATCTGTTCAGGATAAGGATTCAATGCATATNTTGACCGGTC
  GGAATGCATTCTTACAAATGGTTGAAGGACACATGTATAACG
  
  3' Read Nucleotide Sequence

  >Forward primer walk for NM_005192 unedited
  CGATGAAGCCGCCCAGTTCAATACAAACAAGTGAGTTTGACTCATCAGATGAAGAGCCTA
  TTGAAGATGAACAGACTCCAATTCATATATCATGGCTATCTTTGTCACGAGTGAATTGTT
  CTCAGTTTCTCGGTTTATGTGCTCTTCCAGGTTGTAAATTTAAAGATGTTAGAAGAAATG
  TCCAAAAAGATACAGAAGAACTAAAGAGCTGTGGTATACAAGACATATTTGTTTTCTGCA
  CCAGAGGGGAACTGTCAAAATATAGAGTCCCAAACCTTCTGGATCTCTACCAGCAATGTG
  GAATTATCACCCATCATCATCCAATCGCAGATGGAGGGACTCCTGACATAGCCCGCTGCT
  GTGAAATAATGGAAGAGCTTACAACCTGCCCTAAAAATTACCGAAAAACCTTAATACACT
  GCTATGGAGGACTTTGGAGATCTTGTCTTGTAGCTGCTTGTCTCCTACTATACCTGTCTG
  ACACAATATCACCAGAGCAAGCCATAGACAGCCTGCGAGACCTAAGAGGATCCGGGGCAA
  TACAGACCATTCAGCAATACAATTATCTTCATGAGTTTCGGGACAAATTAGCTGCACATC
  TATCATCAAGAAGATTCCAATCAAGATCTGTATCAAGATAAAGGAATTTCAATAGCATAT
  ATATGAACATGTCTGAAATGTCAGTTCTCTAGCATAATTTGGATTGAAATGAAACCCCCA
  GTGTTATCAACTTGAAGTAAATGGTCCTGTGCAGATATTCCTAAGGTTTTTGGCCCNNNC
  AAAAANNNAAGAANAAANAACTCCACCCTAATGGGCCCGGGGATGCTGTTTCGGAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_005192
• Insert Size: 850 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005192.2, NP_005183.2
• RefSeq Size: 836 bp
• RefSeq ORF: 639 bp
• Locus ID: 1033
• UniProt ID: Q16667
• Cytogenetics: 14q22.2
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  Transcript Variant: This variant (1) encodes the longest isoform (1).