ITGA11 (NM_012211) Human Untagged Clone

CAT#: SC124146

ITGA11 (untagged)-Human integrin, alpha 11 (ITGA11), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ITGA11
• Synonyms: HsT18964; integrin, alpha 11
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC124146 sequence for NM_012211 edited (data generated by NextGen Sequencing)
  ATGGACCTGCCCAGGGGCCTGGTGGTGGCCTGGGCGCTCAGCCTGTGGCCAGGGTTCACG
  GACACCTTCAACATGGACACCAGGAAGCCCCGGGTCATCCCTGGCTCCAGGACCGCCTTC
  TTTGGCTACACAGTGCAGCAGCACGACATCAGTGGCAATAAGTGGCTGGTCGTGGGCGCC
  CCACTGGAAACCAATGGCTACCAGAAGACGGGAGACGTGTACAAGTGTCCAGTGATCCAC
  GGGAACTGCACCAAACTCAACCTGGGAAGGGTCACCCTGTCCAACGTGTCCGAGCGGAAA
  GACAACATGCGCCTCGGCCTTAGTCTCGCCACCAACCCCAAGGACAACAGCTTCCTGGCC
  TGCAGCCCCCTCTGGTCTCATGAGTGTGGGAGCTCCTACTACACCACAGGGATGTGTTCA
  AGAGTCAACTCCAACTTCAGGTTCTCCAAGACCGTGGCCCCAGCTCTCCAAAGGTGCCAG
  ACCTACATGGACATCGTCATTGTCCTGGATGGCTCCAACAGCATCTACCCCTGGGTGGAG
  GTTCAGCACTTCCTCATCAACATCCTGAAAAAGTTTTACATTGGCCCAGGGCAGATCCAG
  GTTGGAGTTGTGCAGTATGGCGAAGATGTGGTGCATGAGTTTCACCTCAATGACTACAGG
  TCTGTAAAAGATGTGGTGGAAGCTGCCAGCCACATTGAGCAGAGAGGAGGAACAGAGACC
  CGGACGGCATTTGGCATTGAATTTGCACGCTCAGAGGCTTTCCAGAAGGGTGGAAGGAAA
  GGAGCCAAGAAGGTGATGATTGTCATCACAGATGGGGAGTCCCACGACAGCCCAGACCTG
  GAGAAGGTGATCCAGCAAAGCGAAAGAGACAACGTAACAAGATATGCGGTGGCCGTCCTG
  GGCTACTACAACCGCAGGGGGATCAATCCAGAAACTTTTCTAAATGAAATCAAATACATC
  GCCAGTGACCCTGATGACAAGCACTTCTTCAATGTCACTGATGAGGCTGCCTTGAAGGAC
  ATTGTCGATGCCCTGGGGGACAGAATCTTCAGCCTGGAAGGCACCAACAAGAACGAGACC
  TCCTTTGGGCTGGAGATGTCACAGACGGGCTTTTCCTCGCACGTGGTGGAGGATGGGGTT
  CTGCTGGGAGCCGTCGGTGCCTATGACTGGAATGGAGCTGTGCTAAAGGAGACGAGTGCC
  GGGAAGGTCATTCCTCTCCGCGAGTCCTACCTGAAAGAGTTCCCCGAGGAGCTCAAGAAC
  CATGGTGCATACCTGGGGTACACAGTCACATCGGTCGTGTCCTCCAGGCAGGGGCGAGTG
  TACGTGGCCGGAGCCCCCCGGTTCAACCACACGGGCAAGGTCATCCTGTTCACCATGCAC
  AACAACCGGAGCCTCACCATCCACCAGGCTATGCGGGGCCAGCAGATAGGCTCTTACTTT
  GGGAGTGAAATCACCTCGGTGGACATCGACGGCGACGGCGTGACTGATGTCCTGCTGGTG
  GGCGCACCCATGTACTTCAACGAGGGCCGTGAGCGAGGCAAGGTGTACGTCTATGAGCTG
  AGACAGAACCGGTTTGTTTATAACGGAACGCTAAAGGATTCACACAGTTACCAGAATGCC
  CGATTTGGGTCCTCCATTGCCTCAGTTCGAGACCTCAACCAGGATTCCTACAATGATGTG
  GTGGTGGGAGCCCCCCTGGAGGACAACCACGCAGGAGCCATCTACATCTTCCACGGCTTC
  CGAGGCAGCATCCTGAAGACACCTAAGCAGAGAATCACAGCCTCAGAGCTGGCTACCGGC
  CTCCAGTATTTTGGCTGCAGCATCCACGGGCAATTGGACCTCAATGAGGATGGGCTCATC
  GACCTGGCAGTGGGAGCCCTTGGCAACGCTGTGATTCTGTGGTCCCGCCCAGTGGTTCAG
  ATCAATGCCAGCCTCCACTTTGAGCCATCCAAGATCAACATCTTCCACAGAGACTGCAAG
  CGCAGTGGCAGGGATGCCACCTGCCTGGCCGCCTTCCTCTGCTTCACGCCCATCTTCCTG
  GCACCCCATTTCCAAACAACAACTGTTGGCATCAGATACAACGCCACCATGGATGAGAGG
  CGGTATACACCGAGGGCCCACCTGGACGAGGGCGGGGACCGATTCACCAACAGAGCCGTA
  CTGCTCTCCTCCGGCCAGGAGCTCTGTGAGCGGATCAACTTCCATGTCCTGGACACTGCT
  GACTACGTGAAGCCAGTGACCTTCTCAGTCGAGTATTCCCTGGAGGACCCTGACCATGGC
  CCCATGCTGGACGACGGCTGGCCCACCACTCTCAGAGTCTCGGTGCCCTTCTGGAACGGC
  TGCAATGAGGATGAGCACTGTGTCCCTGACCTTGTGTTGGATGCCCGGAGTGACCTGCCC
  ACGGCCATGGAGTACTGCCAGAGGGTGCTGAGGAAGCCTGCGCAGGACTGCTCCGCATAC
  ACGCTGTCCTTCGACACCACAGTCTTCATCATAGAGAGCACACGCCAGCGAGTGGCGGTG
  GAGGCCACACTGGAGAACAGGGGCGAGAACGCCTACAGCACGGTCCTAAATATCTCGCAG
  TCGGCAAACCTGCAGTTTGCCAGCTTGATCCAGAAGGAGGACTCAGACGGTAGCATTGAG
  TGTGTGAACGAGGAGAGGAGGCTCCAGAAGCAAGTCTGCAACGTCAGCTATCCCTTCTTC
  CGGGCCAAGGCCAAGGTGGCTTTCCGTCTTGATTTTGAGTTCAGCAAATCCATCTTCCTA
  CACCACCTGGAGATCGAGCTCGCTGCAGGCAGTGACAGTAATGAGCGGGACAGCACCAAG
  GAAGACAACGTGGCCCCCTTACGCTTCCACCTCAAATACGAGGCTGACGTCCTCTTCACC
  AGGAGCAGCAGCCTGAGCCACTATGAGGTCAAGCCCAACAGCTCGCTGGAGAGATACGAT
  GGTATCGGGCCTCCCTTCAGCTGCATCTTCAGGATCCAGAACTTGGGCTTGTTCCCCATC
  CACGGGATGATGATGAAGATCACCATTCCCATCGCCACCAGGAGCGGCAACCGCCTACTG
  AAGCTGAGGGACTTCCTCACGGACGAGGCGAACACGTCCTGTAACATCTGGGGCAATAGC
  ACTGAGTACCGGCCCACCCCAGTGGAGGAAGACTTGCGTCGTGCTCCACAGCTGAATCAC
  AGCAACTCTGATGTTGTCTCCATCAACTGCAATATACGGCTGGTCCCCAACCAGGAAATC
  AATTTCCATCTACTGGGGAACCTGTGGTTGAGGTCCCTAAAAGCACTCAAGTACAAATCC
  ATGAAAATCATGGTCAACGCAGCCTTGCAGAGGCAGTTCCACAGCCCCTTCATCTTCCGT
  GAGGAGGATCCCAGCCGCCAGATCGTGTTTGAGATCTCCAAGCAAGAGGACTGGCAGGTC
  CCCATCTGGATCATTGTAGGCAGCACCCTGGGGGGCCTCCTACTGCTGGCCCTGCTGGTC
  CTGGCACTGTGGAAGCTCGGCTTCTTTAGAAGTGCCAGGCGCAGGAGGGAGCCTGGTCTG
  GACCCCACCCCCAAAGTGCTGGAGTGA
  
  Clone variation with respect to NM_012211.3
  651 c=>t;1317 g=>a;1571 t=>g;1677 c=>t;2583 a=>g;2904 c=>t;3195 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012211 unedited
  TAACGTCAAATATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACCAGAGGCGC
  CGCGCCGAGGAGGCTGCCGCTCTGGCTTGCCGCCCCCCGCCGCCGCTGCACACCGGACCC
  AGCCGCCGTGCCGCGGGCCATGGACCTGCCCAGGGGCCTGGTGGTGGCCTGGGCGCTCAG
  CCTGTGGCCAGGGTTCACGGACACCTTCAACATGGACACCAGGAAGCCCCGGGTCATCCC
  TGGCTCCAGGACCGCCTTCTTTGGCTACACAGTGCAGCAGCACGACATCAGTGGCAATAA
  GTGGCTGGTCGTGGGCGCCCCACTGGAAACCAATGGCTACCAGAAGACGGGAGACGTGTA
  CAAGTGTCCAGTGATCCACGGGAACTGCACCAAACTCAACCTGGGAAGGGTCACCCTGTC
  CAACGTGTCCGAGCGGAAAGACAACATGCGCCTCGGCCTTAGTCTCGCCACCAACCCCAA
  GGACAACAGCTTCCTGGCCTGCAGCCCCCTCTGGTCTCATGAGTGTGGGAGCTCCTACTA
  CACCACAGGGATGTGTTCAAGAGTCAACTCCAACTTCAGGTTCTCCAAGACCGTGGCCCC
  AGCTCTCCAAAGGTGCCAGACCTACATGGACATCGTCATTGTCCTGGATGGCTCCAACAG
  CATCTACCCCTGGGTGGAGGTTCAGCACTTCCTCATCAACATCCTGAAAAAGTTNTACAT
  TGGGCCCAGGCAGATCCAGGTTTGGAGTTGTGCAGTATGGCGAAAATGTGGTGCATGAGT
  TTCACCTCAATGACTACAGGTCTGTAAAAAAGTGTTGGGAGCTGCCACCCCCATTGACAN
  AGAGGAGGAACAGAAACCGGACGGCATTTGCAATTGATTTGAACGCTTAAAGCTTTCCAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012211 unedited
  CGCTAATTCCTGTCTGGTGTCCACACCANGCTCCCTCCTGCGCCTGGCACTTCTAAAGAA
  GCCGAGCTTCCACAGTGCCATGTTCAGCAGGGCCAGCAGTAGGAGGCCCCCCAGGGTGCT
  GCCTACTATGATCCAGATGGGGACCTGCCAGTCCTCTTGCTTGGAGATCTCAAACACGAT
  CTGGCGGCTGGGATCCTCCTCACGGAAGATGAAGGGGCTGTGGAACTGCCTCTGCAAGGC
  TGCGTTGACCATGATTTTCATGGATTTGTACTTGAGTGCTTTTAGGGACCTCAACCACAG
  GTTCCCCAGTAGATGGAAATTGATTTCCTGGTTTGGGGACCAGCCGTATATTGCAGTTGA
  TGGAGACAGNNTCCGAGTTGCTGTGATTCAGCTGTGGAGCACGACGCAAGTCTTCCTCCA
  CTGGAGGGGGCCGGTACTCAGAGCTATTGCCCCAAATGTTACTCGACGTGTTCTCTTCAT
  CCGCGATGAACTCCCTCAGCTTCGTATGCGGTTGCCGCTCCTCGTGGCGATGGGAACGGT
  GATCTCCATTATCATCCCGGGGATGGGGAACAAGCCCAAGTTCTGGATCCTGAAGATGCA
  CCTGAAGGGAGGCCCGGATCCATCGTATTTCTCCTACCAGCTGTGTGGGCTTGACCTCAT
  AGTGGCTCAGGCTGCTGCTCCTGGTGAAGAGGACGCCCGCCTTATATTTTGAGGTGGAAA
  CCGTAAGGAGGCCACGTTGTCTTCCTTGGCGCTGACCCGCTGAGAGGGACG
  
• Restriction Sites: Please inquire
• ACCN: NM_012211
• Insert Size: 3200 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_012211.3, NP_036343.3
• RefSeq Size: 5005 bp
• RefSeq ORF: 3567 bp
• Locus ID: 22801
• Cytogenetics: 15q23
• Domains: FG-GAP, VWA
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton
• Gene Summary: This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1 and 2 encode the same protein.