ING1 (NM_198219) Human Untagged Clone

CAT#: SC124139

ING1 (untagged)-Human inhibitor of growth family, member 1 (ING1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ING1
• Synonyms: p24ING1c; p33; p33ING1; p33ING1b; p47; p47ING1a
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC124139 sequence for NM_198219 edited (data generated by NextGen Sequencing)
  ATGTTGAGTCCTGCCAACGGGGAGCAGCTCCACCTGGTGAACTATGTGGAGGACTACCTG
  GACTCCATCGAGTCCCTGCCTTTCGACTTGCAGAGAAATGTCTCGCTGATGCGGGAGATC
  GACGCGAAATACCAAGAGATCCTGAAGGAGCTAGACGAGTGCTACGAGCGCTTCAGTCGC
  GAGACAGACGGGGCGCAGAAGCGGCGGATGCTGCACTGTGTGCAGCGCGCGCTGATCCGC
  AGCCAGGAGCTGGGCGACGAGAAGATCCAGATCGTGAGCCAGATGGTGGAGCTGGTGGAG
  AACCGCACGCGGCAGGTGGACAGCCACGTGGAGCTGTTCGAGGCGCAGCAGGAGCTGGGC
  GACACAGCGGGCAACAGCGGCAAGGCTGGCGCGGACAGGCCCAAAGGCGAGGCGGCAGCG
  CAGGCTGACAAGCCCAACAGCAAGCGCTCACGGCGGCAGCGCAACAACGAGAACCGTGAG
  AACGCGTCCAGCAACCACGACCACGACGACGGCGCCTCGGGCACACCCAAGGAGAAGAAG
  GCCAAGACCTCCAAGAAGAAGAAGCGCTCCAAGGCCAAGGCGGAGCGAGAGGCGTCCCCT
  GCCGACCTCCCCATCGACCCCAACGAACCCACGTACTGTCTGTGCAACCAGGTCTCCTAT
  GGGGAGATGATCGGCTGCGACAACGACGAGTGCCCCATCGAGTGGTTCCACTTCTCGTGC
  GTGGGGCTCAATCATAAACCCAAGGGCAAGTGGTACTGTCCCAAGTGCCGGGGGGAGAAC
  GAGAAGACCATGGACAAAGCCCTGGAGAAATCCAAAAAAGAGAGGGCTTACAACAGGTAG
  
  Clone variation with respect to NM_198219.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_198219 unedited
  CGTCANAATTTGTATACGACTCATATAGGCGGCCGCGAATTCGCACGAGCTGATGTTTCC
  CAGTGTTTGAAACTGGTATTTGGGTTTTCCACGTTGGACAAGTGCGGCTCGGCGGCCAGC
  GGAGCGCGCCCCTTCCCGCTGCCCGCTCCGCTCCTCTCTTCTACCCAGCCCAGTGGGCGA
  GTGGGCAGCGGCGGCCGCGGCGCTGGGCCCTCTCCCGCCGGTGTGTGCGCGCTCGTACGC
  GCGGCCCCCGGCGCCAGCCCCGCCGCCTGAGAGGGGGCCTGCGCCGCCGGCCGGGGCGTG
  CGCCCGGGAGCCACCGCCACCGCGGCCCGCGCCCTCAGGCGCTGGGGTCCCCGCGGACCC
  GGAGGCGGCGGACGGGCTCGGCAGATGTAGCCGCCGGGCCGAAGCAGGAGCCGGCGGGGG
  GGCGCCGGGAGAGCGAGGGCTTTGCATTTTGCAGTGCTATTTTTTGAGGGGGGCGGGGGG
  TGGAGGAAGCGGANAGCCGCGCCGAGTCGCCGGGGACCTCCGGGGTGAACCATGTTGAGT
  CCTGCCAACGGGGAGCAGCTCCACCTGGTGAACTATGTGGAGGACTACCTGGACTCCATC
  GAGTCCTGGGCTTTCGACTTGCAGAGAAAAGGCTCGCTGATGCGGGAGATCAACCCCCAA
  TACCAAGAGATCCCGAAGGGACCTAAAAAAGGCCAAAAACGCCTTAATTCCGAAAAAAAC
  GGGCCCAAAAACCGCGAAGCTGAATGGGGGCACCGCGCCCTTATCCGCACCAGAAACTGG
  GACAAAAAAATCCAATTGGAGCCAAAGGGGAACCGGGGGAAAACCAAACCGGAAGTGGAA
  ACAAGTGGAACTTGTTAGGCGCAAAAGACTGGGGGAACAAGAGAAAAAATATGTGATTGC
  T
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_198219 unedited
  CTTCCACGGCCAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTC
  AGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTT
  TTTTTTGTGGTCCGCTGAAACTTTATTTATGGACACTAGAATTTAAACTTCATATAATGT
  TCAAACAGATGGTGGGCTGAACTTGACAAGTGGGCAGTAATTTCCTGACCCAGGGTCTGA
  ATACAGATTCTTTTTTGACACGTATTTATTTGCTGGCAATTAAGTAACTTCTACTTCATT
  ATTAATAATAAGTGAGAACAATAATACAAAATTTGCTTAAGGCTTTGTCTAAATTGCTGG
  TGTATAAATTTTTAAGACAAATTTTAAAAGTTACTTATGTCAAAATTAAATATACTACTA
  GAGGAACAAACTGGCCAAGTTTCATTTATTTCTTCACGTAACATTTTTACAGCTCACATA
  CAGCAGGAAGCACACCTTTGCACATAATTGTGACATTAGCTTCACAACAGCATCTGCTGA
  CTGCACTTCCAATTATAATATAACAAGTGCAAGTTCATTTGGAAATGTACATTTATACAC
  CTGATATAAATTAAAGATGGGTACACTATGATTGGTGATAGCAAAAGCATGACTTGAGGT
  TCCTTGACTAGACCACTTAAGAGAAGTGTACCCAAGCATTTTAAAATGG
  
• Restriction Sites: Please inquire
• ACCN: NM_198219
• Insert Size: 2800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_198219.1, NP_937862.1
• RefSeq Size: 2897 bp
• RefSeq ORF: 840 bp
• Locus ID: 3621
• UniProt ID: Q9UK53
• Cytogenetics: 13q34
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) differs in the 5' end-region, which includes part of the coding region, compared to variant 4. The resulting isoform (A) has a distinct and shorter N-terminus, as compared to isoform D.