PIP5K2 beta (PIP4K2B) (NM_138687) Human Untagged Clone

CAT#: SC124045

PIP5K2B (untagged)-Human phosphatidylinositol-4-phosphate 5-kinase, type II, beta (PIP5K2B), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PIP5K2 beta
• Synonyms: Pip4k2B, PIP5KIIB
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_138687, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCGTCCAACTGCACCAGCACCACGGCGGTGGCGGTGGCGCCGCTCAGCGCCAGCAAGACCAAGACCA
  AGAAGAAGCATTTCGTGTGCCAGAAAGTGAAGCTATTCCGGGCCAGCGAGCCGATCCTCAGCGTCCTGAT
  GTGGGGGGTGAACCACACGATCAATGAGCTGAGCAATGTTCCTGTTCCTGTCATGCTAATGCCAGATGAC
  TTCAAAGCCTACAGCAAGATCAAGGTGGACAATCATCTCTTCAATAAGGAGAACCTGCCCAGCCGCTTTA
  AGTTTAAGGAGTATTGCCCCATGGTGTTCCGAAACCTTCGGGAGAGGTTTGGAATTGATGATCAGGATTA
  CCAGAATTCAGTGACGCGCAGCGCCCCCATCAACAGTGACAGCCAGGGTCGGTGTGGCACGCGTTTCCTC
  ACCACCTACGACCGGCGCTTTGTCATCAAGACTGTGTCCAGCGAGGACGTGGCGGAGATGCACAACATCT
  TAAAGAAATACCACCAGTTTATAGTGGAGTGTCATGGCAACACGCTTTTGCCACAGTTCCTGGGCATGTA
  CCGCCTGACCGTGGATGGTGTGGAAACCTACATGGTGGTTACCAGGAACGTGTTCAGCCATCGGCTCACT
  GTGCATCGCAAGTATGACCTCAAGGGTTCTACGGTTGCCAGAGAAGCGAGCGACAAGGAGAAGGCCAAGG
  ACTTGCCAACATTCAAAGACAATGACTTCCTCAATGAAGGGCAGAAGCTGCATGTGGGAGAGGAGAGTAA
  AAAGAACTTCCTGGAGAAACTGAAGCGGGACGTTGAGGAGATTCTCGTTCTGTCCCCAGGCTGGAGAATC
  GCTTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_138687 unedited
  GATTTTGAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCGGGGGTGGGGAT
  CGGTCCGGGGGAGGCCTGAGGCCGCTGGCTTGTGCGCTGTCTCCGCCGCCCCCCTGTTTC
  GCCGCCGCCGCCGCCGCCCCGGGCATGTCGTCCAACTGCACCAGCACCACGGCGGTGGCG
  GTGGCGCCGCTCAGCGCCAGCAAGACCAAGACCAAGAAGAAGCATTTCGTGTGCCAGAAA
  GTGAAGCTATTCCGGGCCAGCGAGCCGATCCTCAGCGTCCTGATGTGGGGGGTGAACCAC
  ACGATCAATGAGCTGAGCAATGTTCCTGTTCCTGTCATGCTAATGCCAGATGACTTCAAA
  GCCTACAGCAAGATCAAGGTGGACAATCATCTCTTCAATAAGGAGAACCTGCCCAGCCGC
  TTTAAGTTTAAGGAGTATTGCCCCATGGTGTTCCGAAACCTTCGGGAGAGGTTTGGAATT
  GATGATCAGGATTACCAGAATTCAGTGACGCGCAGCGCCCCCATCAACAGTGACAGCCAG
  GGTCGGTGTGGCACGCGTTTCCTCACCACCTACGACCGGCGCTTTGTCATCAAGACTGTG
  TCCAGCGAGGACGTGGCGGAGATGCACAACATCTTAAAGAAATACCACCAGTTTATAGTG
  GAGTGTCATGGCAACACGCTTTTGCCACAGTTTCTGGGCATGTACCGNCTGACCCGTGGA
  TGGTGTGGAAACCTACATTGGGGGGATCACCAAAAAAGGGTGTAACCATCGGGTCCATTG
  GGCGCTCGCAAGTTTACACCCACAGGGTGTTTTCGTTGTGCTCCAAAAAAGAGCCACAAG
  GAAGAAGCCGGATTTTTCGCCTTTTTTAAAGAAAGAGTTTTCCTATAAAAAGGAAAACCT
  CGTGTTGGGAGAAGAAAAAAAAAAAAAACCTCCGACCCAA
  
• Restriction Sites: Please inquire
• ACCN: NM_138687
• Insert Size: 1800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_138687.1, NP_619632.1
• RefSeq Size: 1486 bp
• RefSeq ORF: 846 bp
• Locus ID: 8396
• Cytogenetics: 17q12
• Domains: PIP5K
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis, Fc gamma R-mediated phagocytosis, Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, Regulation of actin cytoskeleton
• Gene Summary: The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) contains alternate 3' exons as compared to transcript variant 1. As a result, variant 2 encodes isoform b, which is shorter and contains a different C-terminus than isoform a encoded by variant 1.