STRA6 (NM_022369) Human Untagged Clone

CAT#: SC123973

STRA6 (untagged)-Human stimulated by retinoic acid gene 6 homolog (mouse) (STRA6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STRA6
• Synonyms: MCOPCB8; MCOPS9; PP14296
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC123973 sequence for NM_022369 edited (data generated by NextGen Sequencing)
  ATGTCGTCCCAGCCAGCAGGGAACCAGACCTCCCCCGGGGCCACAGAGGACTACTCCTAT
  GGCAGCTGGTACATCGATGAGCCCCAGGGGGGCGAGGAGCTCCAGCCAGAGGGGGAAGTG
  CCCTCCTGCCACACCAGCATACCACCCGGCCTGTACCACGCCTGCCTGGCCTCGCTGTCA
  ATCCTTGTGCTGCTGCTCCTGGCCATGCTGGTGAGGCGCCGCCAGCTCTGGCCTGACTGT
  GTGCGTGGCAGGCCCGGCCTGCCCAGCCCTGTGGATTTCTTGGCTGGGGACAGGCCCCGG
  GCAGTGCCTGCTGCTGTTTTCATGGTCCTCCTGAGCTCCCTGTGTTTGCTGCTCCCCGAC
  GAGGACGCATTGCCCTTCCTGACTCTCGCCTCAGCACCCAGCCAAGATGGGAAAACTGAG
  GCTCCAAGAGGGGCCTGGAAGATACTGGGACTGTTCTATTATGCTGCCCTCTACTACCCT
  CTGGCTGCCTGTGCCACGGCTGGCCACACAGCTGCACACCTGCTCGGCAGCACGCTGTCC
  TGGGCCCACCTTGGGGTCCAGGTCTGGCAGAGGGCAGAGTGTCCCCAGGTGCCCAAGATC
  TACAAGTACTACTCCCTGCTGGCCTCCCTGCCTCTCCTGCTGGGCCTCGGATTCCTGAGC
  CTTTGGTACCCTGTGCAGCTGGTGAGAAGCTTCAGCCGTAGGACAGGAGCAGGCTCCAAG
  GGGCTGCAGAGCAGCTACTCTGAGGAATATCTGAGGAACCTCCTTTGCAGGAAGAAGCTG
  GGAAGCAGCTACCACACCTCCAAGCATGGCTTCCTGTCCTGGGCCCGCGTCTGCTTGAGA
  CACTGCATCTACACTCCACAGCCAGGATTCCATCTCCCGCTGAAGCTGGTGCTTTCAGCT
  ACACTGACAGGGACGGCCATTTACCAGGTGGCCCTGCTGCTGCTGGTGGGCGTGGTACCC
  ACTATCCAGAAGGTGAGGGCAGGGGTCACCACGGATGTCTCCTACCTGCTGGCCGGCTTT
  GGAATCGTGCTCTCCGAGGACAAGCAGGAGGTGGTGGAGCTGGTGAAGCACCATCTGTGG
  GCTCTGGAAGTGTGCTACATCTCAGCCTTGGTCTTGTCCTGCTTACTCACCTTCCTGGTC
  CTGATGCGCTCACTGGTGACACACAGGACCAACCTTCGAGCTCTGCACCGAGGAGCTGCC
  CTGGACTTGAGTCCCTTGCATCGGAGTCCCCATCCCTCCCGCCAAGCCATATTCTGTTGG
  ATGAGCTTCAGTGCCTACCAGACAGCCTTTATCTGCCTTGGGCTCCTGGTGCAGCAGATC
  ATCTTCTTCCTGGGAACCACGGCCCTGGCCTTCCTGGTGCTCATGCCTGTGCTCCATGGC
  AGGAACCTCCTGCTCTTCCGTTCCCTGGAGTCCTCGTGGCCCTTCTGGCTGACTTTGGCC
  CTGGCTGTGATCCTGCAGAACATGGCAGCCCATTGGGTCTTCCTGGAGACTCATGATGGA
  CACCCACAGCTGACCAACCGGCGAGTGCTCTATGCAGCCACCTTTCTTCTCTTCCCCCTC
  AATGTGCTGGTGGGTGCCATGGTGGCCACCTGGCGAGTGCTCCTCTCTGCCCTCTACAAC
  GCCATCCACCTTGGCCAGATGGACCTCAGCCTGCTGCCACCGAGAGCCGCCACTCTCGAC
  CCCGGCTACTACACGTACCGAAACTTCTTGAAGATTGAAGTCAGCCAGTCGCATCCAGCC
  ATGACAGCCTTCTGCTCCCTGCTCCTGCAAGCGCAGAGCCTCCTACCCAGGACCATGGCA
  GCCCCCCAGGACAGCCTCAGACCAGGGGAGGAAGACGAAGGGATGCAGCTGCTACAGACA
  AAGGACTCCATGGCCAAGGGAGCTAGGCCCGGGGCCAGCCGCGGCAGGGCTCGCTGGGGT
  CTGGCCTACACGCTGCTGCACAACCCAACCCTGCAGGTCTTCCGCAAGACGGCCCTGTTG
  GGTGCCAATGGTGCCCAGCCCTGA
  
  Clone variation with respect to NM_022369.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022369 unedited
  CATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGAGGCTGGGGGA
  GGGGCTCAAGGGAGCCCAGCTGGGAGGGCCCAGGCAGGCAGTGCGGAGCTGGCCGTGGGC
  TGCCTACCCTTTCATCTCTGCAACTCCTTCCTCCCTGGGCCTCCCTTCTGGAGAAGGGCC
  AGAGAATGTCGTCCCAGCCAGCAGGGAACCAGACCTCCCCCGGGGCCACAGAGGACTACT
  CCTATGGCAGCTGGTACATCGATGAGCCCCAGGGGGGCGAGGAGCTCCAGCCAGAGGGGG
  AAGTGCCCTCCTGCCACACCAGCATACCACCCGGCCTGTACCACGCCTGCCTGGCCTCGC
  TGTCAATCCTTGTGCTGCTGCTCCTGGCCATGCTGGTGAGGCGCCGCCAGCTCTGGCCTG
  ACTGTGTGCGTGGCAGGCCCGGCCTGCCCAGCCCTGTGGATTTCTTGGCTGGNGACAGGC
  CCCGGGCAGTGCCTGCTGCTGTTTTTCATGTGCCTCCTGAGCCCCCCTGTGTGTGCGCGG
  TTCCCCGACGAGGACGCATTGCCCTTTCTGACTCTCGCCTCAGCACCCAGCCAAGATGGG
  AAAACTGAGGCTCCAAGAGGGGCCTGGAAGATACTGGGACTGGTCTATTATGCTGCCCTC
  TACTACCCTCTGGCTGCCTGTGCCACGGCTGGCCACACAACTGCACACCTGCTCGGCAGC
  ACGCTGTCCTGGGCCCACCTTGGGGTTCCAGTCTTGCCNAAGGCA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_022369 unedited
  CCGTGCAACTTCCGGGCCAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGA
  TCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTGGTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCCCAGGAACAAGTTTATTGCAGGGAA
  CACACTAACCTCTTTCATAATACCCAAAGGCATAAAAACTACAAAAATATCTGGCTCTCG
  AGTGTGGGCAGCTCAGTGTGGGACCTGGTCTTGAGTCATGACTTGGGCTGCCCTGCAGGC
  CAAAGGCCCGGGAGCTTTCCGGCCACTCCCCAAAGAGGTCCGTGGCCCTGAGGGGGTGAG
  GAAGTGCCTTGGCTGCTTCCACAGCGTGAAGGCCAAGGCTGAGGTGGACCTGGGCTGGAT
  TGGTTCCAAAAAAGGCTTCATCGAGGCCCTTCAAGGCTGATGGCAAAGCCAGGGTAGGGA
  GACCCCTGGATGTGGCTGCCCTGGCTCAACTGGCTCCTGGACCAAGGCCCTAACCCACCA
  GTTTTTTTCTCCAAAACCCCTGCTGGCTCTCCCATAGCCAAGTGGGTGGAGCAGAGCCCT
  CCTGAGGCTCCCAGTGCAAACAGACCTCCCCCCAACCCAGTTGTTCCGGAAGACCTGTTG
  GCTGCATGGCTTGGGTAATCCTGGAAGGAAACCCGGGAGGGAGGAGGTTGTAGGCAAGAA
  CATTGCTCAACCAAGATGGCAGGTGGGTGGCCTTCCTGCCTCAGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_022369
• Insert Size: 2800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_022369.2, NP_071764.2
• RefSeq Size: 2820 bp
• RefSeq ORF: 2004 bp
• Locus ID: 64220
• UniProt ID: Q9BX79
• Cytogenetics: 15q24.1
• Protein Families: Transmembrane
• Gene Summary: The protein encoded by this gene is a membrane protein involved in the metabolism of retinol. The encoded protein acts as a receptor for retinol/retinol binding protein complexes. This protein removes the retinol from the complex and transports it across the cell membrane. Defects in this gene are a cause of syndromic microphthalmia type 9 (MCOPS9). Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 8. The resulting isoform (a) is shorter at the N-terminus compared to isoform f. Variants 1, 2, and 3 all encode the same isoform (a).