VEGFD (NM_004469) Human Untagged Clone

CAT#: SC122680

FIGF (untagged)-Human c-fos induced growth factor (vascular endothelial growth factor D) (FIGF)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VEGFD
• Synonyms: FIGF; VEGF-D
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004469 edited
  CAAAAAAGTTTCAATCCAGAGTTGGGTTCCAGCTTTCTGTAGCTGTAAGCATTGGTGGCC
  ACACCACCTCCTTACAAAGCAACTAGAACCTGCGGCATACGTTGGAGAGATTTTTTTAAT
  TTTCTGGACATGAAGTAAATTTAGAGTGCTTTCTAATTTCAGGTAGAAGACATGTCCACC
  TTCTGATTATTTTTGGAGCATGAGAACATTTTGATTTTTTTCATCTCTCTCTCCCCACCC
  CTAAGATTGTGCAAAAAAAGCGTACCTTGCCTAATTGAAATAATTTCATTGGATTTTGAT
  CAGAACTGATTATTTGGTTTTCTGTGTGAAGTTTTGAGGTTTCAAACTTTCCTTCTGGAG
  AATGCCTTTTGAAACAATTTTCTCTAGCTGCCTGATGTCAACTGCTTAGTAATCAGTGGA
  TATTGAAATATTCAAAATGTACAGAGAGTGGGTAGTGGTGAATGTTTTCATGATGTTGTA
  CGTCCAGCTGGTGCAGGGCTCCAGTAATGAACATGGACCAGTGAAGCGATCATCTCAGTC
  CACATTGGAACGATCTGAACAGCAGATCAGGGCTGCTTCTAGTTTGGAGGAACTACTTCG
  AATTACTCACTCTGAGGACTGGAAGCTGTGGAGATGCAGGCTGAGGCTCAAAAGTTTTAC
  CAGTATGGACTCTCGCTCAGCATCCCATCGGTCCACTAGGTTTGCGGCAACTTTCTATGA
  CATTGAAACACTAAAAGTTATAGATGAAGAATGGCAAAGAACTCAGTGCAGCCCTAGAGA
  AACGTGCGTGGAGGTGGCCAGTGAGCTGGGGAAGAGTACCAACACATTCTTCAAGCCCCC
  TTGTGTGAACGTGTTCCGATGTGGTGGCTGTTGCAATGAAGAGAGCCTTATCTGTATGAA
  CACCAGCACCTCGTACATTTCCAAACAGCTCTTTGAGATATCAGTGCCTTTGACATCAGT
  ACCTGAATTAGTGCCTGTTAAAGTTGCCAATCATACAGGTTGTAAGTGCTTGCCAACAGC
  CCCCCGCCATCCATACTCAATTATCAGAAGATCCATCCAGATCCCTGAAGAAGATCGCTG
  TTCCCATTCCAAGAAACTCTGTCCTATTGACATGCTATGGGATAGCAACAAATGTAAATG
  TGTTTTGCAGGAGGAAAATCCACTTGCTGGAACAGAAGACCACTCTCATCTCCAGGAACC
  AGCTCTCTGTGGGCCACACATGATGTTTGACGAAGATCGTTGCGAGTGTGTCTGTAAAAC
  ACCATGTCCCAAAGATCTAATCCAGCACCCCAAAAACTGCAGTTGCTTTGAGTGCAAAGA
  AAGTCTGGAGACCTGCTGCCAGAAGCACAAGCTATTTCACCCAGACACCTGCAGCTGTGA
  GGACAGATGCCCCTTTCATACCAGACCATGTGCAAGTGGCAAAACAGCATGTGCAAAGCA
  TTGCCGCTTTCCAAAGGAGAAAAGGGCTGCCCAGGGGCCCCACAGCCGAAAGAATCCTTG
  ATTCAGCGTTCCAAGTTCCCCATCCCTGTCATTTTTAACAGCATGCTGCTTTGCCAAGTT
  GCTGTCACTGTTTTTTTCCCAGGTGTTAAAAAAAAAAATCCATTTTACACAGCACCACAG
  TGAATCCAGACCAACCTTCCATTCACACCAGCTAAGGAGTCCCTGGTTCATTGATGGATG
  TCTTCTAGCTGCAGATGCCTCTGCGCACCAAGGAATGGAGAGGAGGGGACCCATGTAATC
  CTTTTGTTTAGTTTTGTTTTTGTTTTTTGGTGAATGAGAAAGGTGTGCTGGTCATGGAAT
  GGCAGGTGTCATATGACTGATTACTCAGAGCAGATGAGGAAAACTGTAGTCTCTGAGTCC
  TTTGCTAATCGCAACTCTTGTGAATTATTCTGATTCTTTTTTATGCAGAATTTGATTCGT
  ATGATCAGTACTGACTTTCTGATTACTGTCCAGCTTATAGTCTTCCAGTTTAATGAACTA
  CCATCTGATGTTTCATATTTAAGTGTATTTAAAGAAAATAAACACCATTATTCAAGCCAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004469 unedited
  GCTCTTGTTTTGTAATACGACTTACTATTAGTGGCGGCCGCGATTCCCGGGATCAAAAAA
  TTTCAATCCAGAGTTGGGTTCCAGCTTTCTGTAGCTGTAAGCATTGGTGGCCACACCACC
  TCCTTACAAAGCAACTAGAACCTGCGGCATACGTTGGAGAGATTTTTTTAATTTTCTGGA
  CATGAAGTAAATTTAGAGTGCTTTCTAATTTCAGGTAGAAGACATGTCCACCTTCTGATT
  ATTTTTGGAGCATGAGAACATTTTGATTTTTTTCATCTCTCTCTCCCCACCCCTAAGATT
  GTGCAAAAAAAGCGTACCTTGCCTAATTGAAATAATTTCATTGGATTTTGATCAGAACTG
  ATTATTTGGTTTTCTGTGTGAAGTTTTGAGGTTTCAAACTTTCCTTCTGGAGAATGCCTT
  TTGAAACAATTTTCTCTAGCTGCCTGATGTCAACTGCTTAGTAATCAGTGGATATTGAAA
  TATTCAAAATGTACAGAGAGTGGGTAGTGGTGAATGTTTTCATGATGTTGTACGTCCAGC
  TGGTGCAGGGCTCCAGTAATGAACATGGACCAGTGAAGCGATCATCTCAGTCCACATTGG
  AACGATCTGAACAGCAGATCATGGCTGCTTCTAGTTTGGAGGAACTACTTCGAATTACTC
  ACTCTGAGGACTGGAAGCTGTGGAGATGCAGGCTGAGGCTCAAAAGTTTTACCAGTATGG
  ACTCTCGCTCATCATCCCATCGGTCCACTAGGTTTGCGGCAACTTTCTATGACATTGAAA
  CACTAAAAGTTATAGATGAAGAATGGCAAAGAACTCAGTGCAGCCCTAGAGAAACGTGCG
  TGGNAGTGGCCAGTGAGCTGGGGAAGAGTACCACACATTCTTCAGCCCCCTGTGTNGACG
  TGTTTCGATGTGGTGGCTGGTGCAATGAAAGAGCCTTATCTGGATGAACACCG
  
• Restriction Sites: Please inquire
• ACCN: NM_004469
• Insert Size: 2106 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004469.2, NP_004460.1
• RefSeq Size: 2128 bp
• RefSeq ORF: 1065 bp
• Locus ID: 2277
• UniProt ID: O43915
• Cytogenetics: Xp22.2
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma
• Gene Summary: The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011]