Kallikrein 10 (KLK10) (NM_002776) Human Untagged Clone

CAT#: SC122634

KLK10 (untagged)-Human kallikrein-related peptidase 10 (KLK10), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Kallikrein 10
• Synonyms: NES1; PRSSL1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002776 edited
  CATCCTGCCACCCCTAGCCTTGCTGGGGACGTGAACCCTCTCCCCGCGCCTGGGAAGCCT
  TCTTGGCACCGGGACCCGGAGAATCCCCACGGAAGCCAGTTCCAAAAGGGATGAAAAGGG
  GGCGTTTCGGGCACTGGGAGAAGCCTGTATTCCAGGGCCCCTCCCAGAGCAGGAATCTGG
  GACCCAGGAGTGCCAGCCTCACCCACGCAGATCCTGGCCATGAGAGCTCCGCACCTCCAC
  CTCTCCGCCGCCTCTGGCGCCCGGGCTCTGGCGAAGCTGCTGCCGCTGCTGATGGCGCAA
  CTCTGGGCCGCAGAGGCGGCGCTGCTCCCCCAAAACGACACGCGCTTGGACCCCGAAGCC
  TATGGCGCCCCGTGCGCGCGCGGCTCGCAGCCCTGGCAGGTCTCGCTCTTCAACGGCCTC
  TCGTTCCACTGCGCGGGTGTCCTGGTGGACCAGAGTTGGGTGCTGACGGCCGCGCACTGC
  GGAAACAAGCCACTGTGGGCTCGAGTAGGGGATGACCACCTGCTGCTTCTTCAGGGCGAG
  CAGCTCCGCCGGACGACTCGCTCTGTTGTCCATCCCAAGTACCACCAGGGCTCAGGCCCC
  ATCCTGCCAAGGCGAACGGATGAGCACGATCTCATGTTGCTAAAGCTGGCCAGGCCCGTA
  GTGCCGGGGCCCCGCGTCCGGGCCCTGCAGCTTCCCTACCGCTGTGCTCAGCCCGGAGAC
  CAGTGCCAGGTTGCTGGCTGGGGCACCACGGCCGCCCGGAGAGTGAAGTACAACAAGGGC
  CTGACCTGCTCCAGCATCACTATCCTGAGCCCTAAAGAGTGTGAGGTCTTCTACCCTGGC
  GTGGTCACCAACAACATGATATGTGCTGGACTGGACCGGGGCCAGGACCCTTGCCAGAGT
  GACTCTGGAGGCCCCCTGGTCTGTGACGAGACCCTCCAAGGCATCCTCTCGTGGGGTGTT
  TACCCCTGTGGCTCTGCCCAGCATCCAGCTGTCTACACCCAGATCTGCAAATACATGTCC
  TGGATCAATAAAGTCATACGCTCCAACTGATCCAGATGCTACGCTCCAGCTGATCCAGAT
  GTTATGCTCCTGCTGATCCAGATGCCCAGAGGCTCCATCGTCCATCCTCTTCCTCCCCAG
  TCGGCTGAACTCTCCCCTTGTCTGCACTGTTCAAACCTCTGCCGCCCTCCACACCTCTAA
  ACATCTCCCCTCTCACCTCATTCCCCCACCTATCCCCATTCTCTGCCTGTACTGAAGCTG
  AAATGCAGGAAGTGGTGGCAAAGGTTTATTCCAGAGAAGCCAGGAAGCCGGTCATCACCC
  AGCCTCTGAGAGCAGTTACTGGGGTCACCCAACCTGACTTCCTCTGCCACTCCCCGCTGT
  GTGACTTTGGGCAAGCCAAGTGCCCTCTCTGAACCTCAGTTTCCTCATCTGCAAAATGGG
  AACAATGACGTGCCTACCTCTTAGACATGTTGTGAGGAGACTATGATATAACATGTGTAT
  GTAAATCTTAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002776 unedited
  AAAGTCANAATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGCATCCT
  GCCACCCCTAGCCTTGCTGGGGACGTGAACCCTCTCCCCGCGCCTGGGAAGCCTTCTTGG
  CACCGGGACCCGGAGAATCCCCACGGAAGCCAGTTCCAAAAGGGATGAAAAGGGGGCGTT
  TCGGGCACTGGGAGAAGCCTGTATTCCAGGGCCCCTCCCAGAGCAGGAATCTGGGACCCA
  GGAGTGCCAGCCTCACCCACGCAGATCCTGGCCATGAGAGCTCCGCACCTCCACCTCTCC
  GCCGCCTCTGGCGCCCGGGCTCTGGCGAAGCTGCTGCCGCTGCTGATGGCGCAACTCTGG
  GCCGCAGAGGCGGCGCTGCTCCCCCAAAACGACACGCGCTTGGACCCCGAAGCCTATGGC
  GCCCCGTGCGCGCGCGGCTCGCAGCCCTGGCAGGTCTCGCTCTTCAACGGCCTCTCGTTC
  CACTGCGCGGGTGTCCTGGTGGACCAGAGTTGGGTGCTGACGGCCGCGCACTGCGGAAAC
  AAGCCACTGTGGGCTCGAGTAGGGGATGACCACCTGCTGCTTCTTCAGGGCGAGCAGCTC
  CGCCGGACGACTCGCTCTGTTGTCCATCCCAAGTACCACCAGGGCTCAGGCCCCATCCTG
  CCAAGGCGAACGGATGAGCACGATCTCATGTTGCTAAAGCTGGCCAGGCCCGTAGTGCCG
  GGGCCCCCGCGTCCGGGCCCTGGAGCTTCCCTACCGCTGTGCTAAGCCCGGAAACAGTGC
  CACGTTGCTGGCTGGGGCACACGGCCGCCCGGAGAGTGAAGTCACCAGGGCCTGAACTGT
  TCCAAATTACTATCCTGAGCCCTTAAAATGTGAAGGGTCTCTCCCCC
  
• Restriction Sites: Please inquire
• ACCN: NM_002776
• Insert Size: 1542 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002776.3, NP_002767.2
• RefSeq Size: 1580 bp
• RefSeq ORF: 831 bp
• Locus ID: 5655
• UniProt ID: O43240
• Cytogenetics: 19q13.41
• Protein Families: Druggable Genome, Protease, Secreted Protein
• Gene Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript. All transcript variants encode the same protein.