TRP1 (TYRP1) (NM_000550) Human Untagged Clone

CAT#: SC119834

TYRP1 (untagged)-Human tyrosinase-related protein 1 (TYRP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRP1
• Synonyms: b-PROTEIN; CAS2; CATB; GP75; OCA3; TRP; TRP1; TYRP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119834 sequence for NM_000550 edited (data generated by NextGen Sequencing)
  ATGAGTGCTCCTAAACTCCTCTCTCTGGGCTGTATCTTCTTCCCCTTGCTACTTTTTCAG
  CAGGCCCGGGCTCAATTCCCAAGACAGTGTGCCACTGTTGAGGCTTTGAGAAGTGGTATG
  TGTTGCCCAGACCTGTCCCCTGTGTCTGGGCCTGGGACAGACCGCTGTGGCTCATCATCA
  GGGAGGGGCAGATGTGAGGCAGTGACTGCAGACTCCCGGCCCCACAGCCCTCAGTATCCC
  CATGATGGCAGAGATGATCGGGAGGTCTGGCCCTTGCGCTTCTTCAATAGGACATGTCAC
  TGCAACGGCAATTTCTCAGGACACAACTGTGGGACGTGCCGTCCTGGCTGGAGAGGAGCT
  GCCTGTGACCAGAGGGTTCTCATAGTCAGGAGAAATCTTCTGGACTTAAGTAAAGAAGAA
  AAGAACCACTTTGTCCGGGCCCTGGATATGGCAAAGCGCACAACTCACCCTTTATTTGTC
  ATTGCCACCAGGAGATCAGAAGAAATACTGGGGCCAGATGGCAACACGCCACAATTTGAG
  AACATTTCCATTTATAACTACTTTGTTTGGACACACTATTACTCAGTCAAAAAGACTTTC
  CTTGGGGTAGGACAGGAAAGCTTTGGTGAAGTGGATTTCTCTCATGAGGGACCAGCTTTT
  CTCACATGGCACAGGTACCACCTCCTGCGTCTGGAGAAAGACATGCAGGAAATGTTGCAA
  GAGCCTTCTTTCTCCCTTCCTTACTGGAATTTTGCAACGGGGAAAAATGTCTGTGATATC
  TGCACGGATGACTTGATGGGATCCAGAAGCAACTTTGATTCCACTCTAATAAGCCCAAAC
  TCTGTCTTTTCTCAATGGCGAGTGGTCTGTGACTCCTTGGAAGATTATGATACCCTGGGA
  ACACTTTGTAACAGCACCGAGGATGGGCCAATTAGGAGAAATCCAGCTGGAAATGTGGCC
  AGACCAATGGTGCAACGTCTTCCTGAACCACAGGATGTCGCTCAGTGCTTGGAAGTTGGT
  TTATTTGACACGCCTCCTTTTTATTCCAACTCTACAAACAGTTTCCGAAACACAGTGGAA
  GGTTACAGTGACCCCACGGGAAAGTATGACCCTGCTGTTCGAAGTCTTCACAATTTGGCT
  CATCTATTCCTGAATGGAACAGGGGGACAAACCCATTTGTCTCCAAATGATCCTATTTTT
  GTCCTCCTGCACACCTTCACAGATGCAGTCTTTGATGAATGGCTGAGGAGATACAATGCT
  GATATATCCACATTTCCATTGGAAAATGCCCCTATTGGACATAATAGACAATACAACATG
  GTGCCATTCTGGCCCCCAGTCACCAACACAGAAATGTTTGTTACTGCTCCAGACAACCTG
  GGATACACTTATGAAATTCAATGGCCAAGTCGGGAGTTTAGTGTACCTGAGATAATTGCC
  ATAGCAGTAGTTGGCGCTTTGTTACTGGTTGCACTCATTTTTGGGACTGCTTCTTATCTG
  ATTCGTGCCAGACGCAGTATGGATGAAGCTAACCAGCCTCTCCTCACTGATCAGTATCAA
  TGCTATGCTGAAGAATATGAAAAACTCCAGAATCCTAATCAGTCTGTGGTCTAA
  
  Clone variation with respect to NM_000550.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000550 unedited
  NGGTCAAAATTTGTATACGACTCCTATAGGGCGGCCGCGATTCGGCACGAGGAAGAAACA
  CAGCAAATATAAAACATTCAATTCTAAGAGAAGTTCATCAGAGACATCCTTCAGGATTGT
  GAGCTGGATTTTCCTCTACGTGCTTCAGTCTTCTCTACACAAAGAGCTGCAAACCAGGTC
  TTTGTTTTGCACTCTTATTTCAAGCAGAATGAGTGCTCCTAAACTCCTCTCTCTGGGCTG
  TATCTTCTTCCCCTTGCTACTTTTTCAGCAGGCCCGGGCTCAATTCCCAAGACAGTGTGC
  CACTGTTGAGGCTTTGAGAAGTGGTATGTGTTGCCCAGACCTGTCCCCTGTGTCTGGGCC
  TGGGACAGACCGCTGTGGCTCATCATCAGGGAGGGGCAGATGTGAGGCAGTGACTGCAGA
  CTCCCGGCCCCACAGCCCTCAGTATCCCCATGATGGCAGAGATGATCGGGAGGTCTGGCC
  CTTGCGCTTCTTCAATAGGACATGTCACTGCAACGGCAATTTCTCAGGACACAACTGTGG
  GACGTGCCGTCCTGGCTGGAGAGGAGCTGCCTGTGACCAGAGGGTTCTCATAGTCAGGAG
  AAATCTTCTGGACTTAAGTAAAGAAGAAAAGAACCACTTTGTCCGGGCCCTGGATATGGC
  AAAGCGCACAACTCACCCTTTATTTGTCATTGCCACCAGGAGATCAGAAGAAATACTGGG
  GCCAGATGGCAACACGCCACAATTTGAGAACATTTCCATTTATAACTANCTTTGTTTGGA
  CACACTATTACTCAGTCAAAAAGACTTTCCTTGGNNGTAGGACAGGNAAGCTTGGNNTGA
  AGNTGGATTTCTCTCATGAGGGACCAGCTTTNCTACATGGCACAGGTACCACCTNCTGCG
  TCTGGNAGAAGACATGCAGAAATGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000550 unedited
  ACGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTAATATGTTAATATTTTACTTGGAA
  AATACATAAAAGGCTGATAAATGATAAGAGAATGCTATTTAAATTAAGCACAGTGATTGG
  AATACTATTTATAGAGCAGTATAAAACATGTTCTCCATATGCCTTCTCCATGGACCTCTA
  AGATGTTAGAAGAGACATTAGTAGGTGAAATGTAAGGATAGGTAGTTCCTTTTTCAGCGA
  ATTGAGAGGCAGGGAAACACAGTGGCAAACACAGGCAATATCCATTGTTGCTTAAGAAAG
  TGAAGATTTTCCCTCTCCAAAGTTTGACAAAGATGGTGATTTTTGTTGTAGCCTTGAACC
  TGAGACTAAATAGTATATGTTGACTAAATAATATATTTGATTGGTCTTCAAACTGGAACA
  TTAATTTGAAAAGGTTAATCAAAATTTCATTGGTTTATAACTACACATAATTTTCTTTAA
  TTAATAACTGAGGTTTTCTTTAAATCTGTTGACAAATATCCATGAATGGAAATGAGTTTA
  TGTTTTAACATTTTAGAAATGCCCATTCATGTATTTTAAGTGGACATTTACTATCAAACA
  TTATTTTCCTTTACACGTAAACAAAGCATGGTAGTTCACTTATATCTTCACATACTCAAC
  CTTTAAATCATGCCAAAGATCTTCACACTATCCCTTAAATATCATGGAGTTTAGTGTCAT
  TCACATTTTTAATAGAACTGAAACTAAAACCCATTGANAAGATTCTGAAGGGTCTTCCAG
  CTTTGAAAGTATGCCTAGAACTCTATNCTAACTATGCTTGGTTAGAAGAAGGCATAAGTG
  AAGAAATCAGTATACCTAATCATATATCAACCAGTGGTTTTGAACTATGCTANGAAGTGG
  CTTTGTAAACCCGACGATAGATCTGGGTTTCATATTCTACTACTGTACGACNGAGAAGCG
  GTACTCACCACGGGGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000550
• Insert Size: 2800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000550.1, NP_000541.1
• RefSeq Size: 2797 bp
• RefSeq ORF: 1614 bp
• Locus ID: 7306
• UniProt ID: P17643
• Cytogenetics: 9p23
• Domains: tyrosinase
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Melanogenesis, Metabolic pathways, Tyrosine metabolism
• Gene Summary: This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. [provided by RefSeq, Mar 2009]